West China Journal of Stomatology ›› 2021, Vol. 39 ›› Issue (2): 123-128.doi: 10.7518/hxkq.2021.02.001

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Advances in biomimetic modification of materials for oromaxillofacial bone regeneration and dental implant

Jiang Xinquan()   

  1. Dept. of Prosthodontics, Shanghai Ninth People, s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; College of Stomatology, Shanghai Jiao Tong University; National Clinical Research Center for Oral Diseases; Shanghai Engineering Research Center of Advanced Dental Technology and Materials; Shanghai Key Laboratory of Stomatology; Shanghai Research Institute of Stomatology, Shanghai 200011, China
  • Received:2020-10-09 Revised:2020-12-18 Online:2021-04-01 Published:2021-04-09
  • Contact: Jiang Xinquan E-mail:xinquanjiang@aliyun.com
  • Supported by:
    Innovation Research Group of National Natural Science Foundation of China(81921002);The National Key Research and Development Program of China(2016YFC1102900);Key International (Regional) Cooperative Research Projects of National Natural Science Foundation of China(81620108006)


Oromaxillofacial hard tissue defects is still a difficult problem in clinical treatment. Regeneration of oromaxillofacial hard tissue based on tissue engineering technology has a good clinical application prospect. The functional modification of scaffolds is one of key factors that influence the outcome of tissue regeneration. The biomimetic design of biomaterials through simulating the natural structure and composition of oromaxillofacial hard tissue has gradually become a research hotspot due to its advantages of simplicity and efficiency. In this article, the biomimetic modification of biomaterials for oromaxillofacial hard tissue regeneration is reviewed, expecting to provide a new idea for the treatment of oromaxillofacial hard tissue defect.

Key words: oromaxillofacial hard tissue, tissue engineering, biomimetic design, micro-nano structure, bioactive ions, cell sheet

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