Effect of histone acetylation on osteogenic differentiation of periodontal ligament stem cells derived from periodontitis tissue

doi:10.7518/hxkq.2019.01.020

Abstract

Abstract:

Epigenetics is defined as a change in gene expression without the alteration of the genetic sequence. Such a change would be inherited by offspring. Histone acetylation is a type of epigenetics. Existing studies proposed that chronic periodontitis is related to epigenetic modification. In this review, we summarised the influence of chronic periodontitis on periodontal ligament stem cells by histone acetylation.

Key words: histone acetylation, chronic periodontitis, periodontal ligament stem cells, osteogenic differentiation

CLC Number:

Q 786

Jin Sun,Yun Liu,Qian Qu,Juan Qu,Wei Luo,Feng Zhang,Min. Wu. Effect of histone acetylation on osteogenic differentiation of periodontal ligament stem cells derived from periodontitis tissue[J]. West China Journal of Stomatology, 2019, 37(1): 102-105.

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