Functions of non-coding RNAs in the osteogenic differentiation of human periodontal ligament-derived cells

doi:10.7518/hxkq.2020.03.018

Abstract

Abstract:

Human periodontal ligament-derived cells serve as an important source of seeding cells in periodontal regenerative medicine, and their osteogenic potential is closely related to alveolar bone repair and periodontal regeneration. Non-coding RNA (ncRNA), such as microRNA, long non-coding RNA, and circular RNA, play important roles in the regulation of osteogenic genes in human periodontal ligament-derived cells. In this review, we summarize the target genes, pathways, and functions of the ncRNA network during osteogenic differentiation of periodontal ligament-derived cells.

Key words: microRNA, long non-coding RNA, circular RNA, periodontal ligament cell, periodontal ligament stem cell, osteogenic differentiation

CLC Number:

Q254

Wen Jiahui, Wu Yanmin, Chen Lili. Functions of non-coding RNAs in the osteogenic differentiation of human periodontal ligament-derived cells[J]. West China Journal of Stomatology, 2020, 38(3): 330-337.

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