华西口腔医学杂志

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人体颞下颌关节关节盘及关节软骨渗透性的研究

徐小川1 , 陈孟诗2 , 易新竹3   

  1. 1.北京市创伤骨科研究所,北京 100035;2.四川大学建筑与环境学院  力学系,四川  成都 610065;3.四川大学华西口腔医院  修复科,四川  成都 610041
  • 收稿日期:2006-06-25 修回日期:2006-06-25 出版日期:2006-06-20 发布日期:2006-06-20
  • 通讯作者: 徐小川,Tel:010-58516782
  • 作者简介:徐小川(1970-),男,重庆人,主治医师,硕士
  • 基金资助:

    国家自然科学基金资助项目(39270725)

Permeability Research of Human Temporomandibular Joint Disc and Cartilage

XU Xiao-chuan1, CHEN Meng-shi2, YI Xin-zhu3   

  1. 1. Beijing Research Institute of Traumatology and Orthopedics, Beijing 100035, China; 2. Dept. of Mechanics, College of Architecture and Circumstance, Sichuan University, Chengdu 610065, China; 3. Dept. of Prosthodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2006-06-25 Revised:2006-06-25 Online:2006-06-20 Published:2006-06-20

摘要:

目的  测量人体颞下颌关节(TMJ)关节盘及关节软骨的渗透性,为口腔生物力学和口腔组织工程提供基本参数,并从生物力学角度探讨其抗力及分散载荷的机制。方法  4具新鲜人尸体TMJ标本按照关节盘、髁突及关节窝取材共制成不同直径(2 mm,3 mm,4 mm)试件128个,使用与试件直径相同的压缩头,以围限压缩方法测量TMJ渗透性。结果  关节各区中关节盘渗透性最大,关节窝渗透性最小。小直径试件比大直径试件渗透性低,随着试件直径的增加,关节盘、髁突和关节窝的渗透性均增加。结论  在正常生理范围内,关节软组织可以通过降低渗透性保护关节组织;关节盘由于具有较大渗透性,是TMJ的薄弱易损区域,关节盘破坏是TMJ损伤的始动因素。

关键词: 围限压缩, 渗透性, 颞下颌关节

Abstract:

 Objective  To measure the permeability of human temporomandibular joint(TMJ) disc and cartilage to provide basic parameter for oral biomechanics and tissue engineering, and analyze its mechanisms of pathology and load-release. Methods  Confined compression method was used to measure the permeability(k value) of four cadavers′ TMJs, which were sampled into three parts: disc, condyle and glenoid fossa with different diameters(2 mm, 3 mm and 4 mm). All 128 samples were tested with correspond diameter indenter. Results  Larger the sample diameter was, higher the k value became. The highest k value appeared in the disc while the lowest appeared in glenoid fossa. Conclusion  In normal condition, TMJ can suffer huge load by decreasing its permeability. Disc is weakest for the higher permeability, it′s easy-damaged region is an initiated factor of TMJ disease.

Key words: confined compression, permeability, temporomandibular joint