华西口腔医学杂志 ›› 2012, Vol. 30 ›› Issue (5): 493-497.doi: 10.3969/j.issn.1000-1182.2012.05.010

• 临床研究 • 上一篇    下一篇

氟对脱矿和再矿化牙釉质表面的影响

吴娜1 周学东2 郝玉庆2   

  1. 1.重庆医科大学附属口腔医院牙体牙髓科; 重庆市口腔疾病与生物医学研究中心, 重庆401147;2.口腔疾病研究国家重点实验室, 四川大学, 成都610041
  • 收稿日期:2011-11-15 修回日期:2012-01-10 出版日期:2012-10-01 发布日期:2012-10-01
  • 通讯作者: 周学东,Tel:028-85501480
  • 作者简介:吴娜(1983—),女,四川人,住院医师,硕士
  • 基金资助:

    国家自然科学基金资助项目(0040305401031);重庆市医学重点学科建设经费基金资助项目(2011)

Effect to demineralization and remineralization of enamel surface by fluorine

Wu Na1, Zhou Xuedong2, Hao Yuqing2   

  1. 1. Dept. of Conservative Dentistry and Endodontics, The Affiliated Hospital of Stomatology, Chongqing Medical University; Chongqing Research Center for Oral Diseases and Biomedical Science, Chongqing 401147, China; 2. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China
  • Received:2011-11-15 Revised:2012-01-10 Online:2012-10-01 Published:2012-10-01

摘要:

目的研究氟对脱矿和再矿化牙釉质表面的影响,探讨氟防龋的作用机理。方法将牛牙釉质标本分为空白对照组(A组)、非氟化组(B组)、低氟化组(C组)和高氟化组(D组)4组,其中低氟化组和高氟化组依次进行氟化实验、脱矿实验和pH循环再矿化实验,非氟化组只进行脱矿实验和pH循环再矿化实验,空白对照组不做处理。在体视显微镜、显微硬度计和扫描电镜下观察各组釉质表面的形态变化,同时测量分析釉质表面显微硬度。结果氟化牙釉质的表面微观形态显著不同,其脱矿损害具有相对完整的表层;氟化组在氟化、脱矿和再矿化后与非氟化组相比,表面显微硬度均有统计学差异(P<0.05)。结论氟化牙釉质可增强牙釉质的抗龋能力和再矿化效能。

关键词: 氟, 釉质, 脱矿, 再矿化

Abstract:

Objective To analyze the mechanism of fluorine by systemic analysis of fluorination-demineralizationremineralization experiments. Methods The enamel specimens were randomly assigned to untreated group(group A), non-fluoride group(group B), low-fluoride group(group C) and high-fluoride group(group D). The in vitro model of fluoride enamel was established in group C and D. Based on that, the establishment of demineralization model and remineralization experiment by pH-cycling in group B, C and D were followed. All enamel specimens were observed by stereomicroscope and scanning electron microscope and compared in surface microhardness value. Results There was distinct difference in micro-morphologic appearance on fluoride enamel surface. Artificial caries of fluoride enamel showed a relatively complete surface, the surface microhardness after demineralization and remineralization in fluoride group was higher than non-fluoride group(P<0.05). Conclusion The fluorinated enamel can enhance cariostatic potential and remineralization capacity of dental enamel.

Key words: fluorine, enamel, demineralization, remineralization