West China Journal of Stomatology ›› 2021, Vol. 39 ›› Issue (2): 164-169.doi: 10.7518/hxkq.2021.02.006
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Xia Xiaoyang1(), Fang Fei1, Liu Yan1, Che Chao1, Ke Jinjuan1, Jiang Shengjun2()
Received:
2020-04-23
Revised:
2021-01-17
Online:
2021-04-01
Published:
2021-04-09
Contact:
Jiang Shengjun
E-mail:2967939793@qq.com;252956991@qq.com
Supported by:
CLC Number:
Xia Xiaoyang, Fang Fei, Liu Yan, Che Chao, Ke Jinjuan, Jiang Shengjun. Expression of cyclophilin A in oral squamous cell carcinoma and its effect on cell proliferation and invasion[J]. West China Journal of Stomatology, 2021, 39(2): 164-169.
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Tab 1
The differences of the expressions of CyPA protein among different clinical indicators of OSCC
指标 | n | CyPA蛋白表达/n(%) | χ2值 | P值 | ||
---|---|---|---|---|---|---|
阳性 | 阴性 | |||||
性别 | 男性 | 46 | 36(78.26) | 10(21.74) | 0.171 | 0.679 |
女性 | 31 | 23(74.19) | 8(25.81) | |||
年龄/岁 | ≥60 | 37 | 27(72.97) | 10(27.03) | 0.530 | 0.467 |
<60 | 40 | 32(80.00) | 8(20.00) | |||
TNM分期 | T1+T2期 | 42 | 28(66.67) | 14(33.33) | 5.114 | 0.024 |
T3+T4期 | 35 | 31(88.57) | 4(11.43) | |||
临床分期 | Ⅰ+Ⅱ期 | 32 | 19(59.38) | 13(40.63) | 9.095 | 0.003 |
Ⅲ+Ⅳ期 | 45 | 40(88.89) | 5(11.11) | |||
分化程度 | 中低分化 | 42 | 38(90.48) | 4(9.52) | 9.899 | 0.002 |
高分化 | 35 | 21(60.00) | 14(40.00) | |||
淋巴结转移 | 是 | 36 | 33(91.67) | 3(8.33) | 7.424 | 0.006 |
否 | 41 | 27(65.85) | 14(34.15) |
Tab 2
Comparison on the proliferation ability of cells in the three groups at different time points
组别 | 24 h | 48 h | 72 h | 96 h |
---|---|---|---|---|
CyPA干扰序列组 | 0.29±0.04ab | 0.35±0.07ab | 0.47±0.10ab | 0.64±0.04ab |
阴性对照组 | 0.42±0.06 | 0.59±0.05 | 0.69±0.03 | 0.87±0.06 |
空白组 | 0.40±0.07 | 0.60±0.03 | 0.72±0.07 | 0.83±0.07 |
F值 | 9.583 | 44.327 | 23.771 | 29.780 |
P值 | 0.002 | <0.001 | <0.001 | <0.001 |
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