Development and homeostasis of taste buds in mammals

doi:10.7518/hxkq.2018.05.016

Abstract

Abstract:

Taste is mediated by multicellular taste buds distributed throughout the oral and pharyngeal cavities. The taste buds can detect five basic tastes: sour, sweet, bitter, salty and umami, allowing mammals to select nutritious foods and avoid the ingestion of toxic and rotten foods. Once developed, the taste buds undergo continuous renewal throughout the adult life. In the past decade, significant progress has been achived in delineating the cellular and molecular mechanisms governing taste buds development and homeostasis. With this knowledges and in-depth investigations in the future, we can achieve the precise management of taste dysfunctions such as dysgeusia and ageusia.

Key words: taste buds, gustatory system, stem cells, development, homeostasis

CLC Number:

Xin Zheng,Xin Xu,Jinzhi He,Ping Zhang,Jiao Chen,Xue-dong Zhou. Development and homeostasis of taste buds in mammals[J]. West China Journal of Stomatology, 2018, 36(5): 552-558.

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