单纯凝血因子Ⅷ补充治愈下颌骨血友病假性肿瘤1例

doi:10.7518/hxkq.2022.04.018

华西口腔医学杂志 ›› 2022, Vol. 40 ›› Issue (4): 489-493.doi: 10.7518/hxkq.2022.04.018

• 病例报告 • 上一篇

单纯凝血因子Ⅷ补充治愈下颌骨血友病假性肿瘤1例

吴娟¹(), 苏吉梅¹(), 叶笑味¹, 徐卫群²

^1.浙江大学医学院附属儿童医院口腔科国家儿童健康与疾病临床医学研究中心，杭州 310052
^2.浙江大学医学院附属儿童医院血液科国家儿童健康与疾病临床医学研究中心，杭州 310052

收稿日期:2021-06-10 修回日期:2022-03-08 出版日期:2022-07-25 发布日期:2022-07-27
通讯作者: 苏吉梅 E-mail:juanjuan1206@zju.edu.cn;6198003@zju.edu.cn
作者简介:吴娟，住院医师，学士，E-mail：juanjuan1206@zju.edu.cn
基金资助:
浙江省教育厅科研项目(Y201432750);浙江省小儿白血病诊治技术研究中心项目(JBZX-201904)

Conservative management with factor Ⅷ replacement alone for hemophilic pseudotumor in the mandible: a case report

Wu Juan¹(), Su Jimei¹(), Ye Xiaowei¹, Xu Weiqun²

^1.Dept. of Stomatology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China
^2.Dept. of Hematology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou 310052, China

Received:2021-06-10 Revised:2022-03-08 Online:2022-07-25 Published:2022-07-27
Contact: Su Jimei E-mail:juanjuan1206@zju.edu.cn;6198003@zju.edu.cn
Supported by:
Scientific Research Project of Department of Education of Zhejiang Province(Y201432750);Pediatric Leukemia Diagnosis and Therapeutic Technology Research Center of Zhejiang Province(JBZX-201904);Correspondence: Su Jimei, E-mail: 6198003@zju.edu.cn

摘要/Abstract

摘要：

血友病假性肿瘤是血友病患者罕见但严重的并发症，发生在下颌骨较少见，治疗不当易导致出血，严重者甚至死亡。本文报道1例发生于右下颌骨血友病（A型）假性肿瘤，伴有广泛性骨破坏，经单纯凝血因子Ⅷ替代治疗后骨破坏修复，随访10年无复发。

关键词: 血友病, 血友病假性肿瘤, 下颌骨, 出血

Abstract:

Hemophilic pseudotumor is a rare but serious complication that occurs less frequently in the jaw, and it may lead to bleed uncontrollably and even death. This paper reported a case of hemophilic pseudotumor with extensive osteo-destruction in the right mandible, treated by factor Ⅷ replacement and with no recurrence after 10 years of follow-up.

Key words: hemophilia, hemophilic pseudotumor, mandible, bleeding

中图分类号:

R 781.6⁺2

吴娟, 苏吉梅, 叶笑味, 徐卫群. 单纯凝血因子Ⅷ补充治愈下颌骨血友病假性肿瘤1例[J]. 华西口腔医学杂志, 2022, 40(4): 489-493.

Wu Juan, Su Jimei, Ye Xiaowei, Xu Weiqun. Conservative management with factor Ⅷ replacement alone for hemophilic pseudotumor in the mandible: a case report[J]. West China Journal of Stomatology, 2022, 40(4): 489-493.

图/表 4

参考文献 30

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单纯凝血因子Ⅷ补充治愈下颌骨血友病假性肿瘤1例

Conservative management with factor Ⅷ replacement alone for hemophilic pseudotumor in the mandible: a case report

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