West China Journal of Stomatology

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Angle′s Class Ⅱ malocclusion: A report of seven cases in one family

ZHANG Xiao-ge1, YANG Fan2, CHEN Lin3, CHEN Song1, CHEN Yang-xi1   

  1. 1. Dept. of Orthodontics, West China College of Stomatology, Sichuan University, Chengdu 610041, China; 2. Division of Peptides Related with Human Diseases, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China; 3. Dept. of Integrated Traditional and Western Medicine, Sichuan Petroleum General Hospital, Chengdu 610213, China
  • Received:2010-04-25 Revised:2010-04-25 Online:2010-04-20 Published:2010-04-20
  • Contact: CHEN Yang-xi,Tel:028-85503477

Abstract:

A family with Angle′s Class Ⅱ malocclusion was identified in West China Stomatological Hospital of Sichuan University. The proband was a 22 -year -old woman with Angle′ s Class Ⅱ Division 2 malocclusion with congenitally missing teeth. A total of 15 members of the 3 generations in the family were investigated. There were 7 members(3 males, 4 females) with Angle′s Class Ⅱ malocclusion in the family. The results provide the primary basis for further study to localize the virulence gene.

Key words: malocclusion, Angle′s Class Ⅱ, pedigree, gene