Advances in salivary protein glycosylation and its relationship with systemic and oral diseases

doi:10.7518/hxkq.2018.03.020

Abstract

Abstract:

Protein glycosylation is one of the most important protein post-translational modifications that can affect life activities by endowing the protein with various structural and functional features. Saliva is an easy-to-obtain, noninvasive body fluid that contains components originating from serum, gingival crevicular fluid, and oropharyngeal mucosae. In recent years, understanding of saliva has been constantly updated with the developments in related research. Studies have shown that salivary proteins can be used as diagnostic markers for certain diseases, and changes of protein glycosylation in saliva are generally considered to be related to many diseases. In this review, salivary protein glycosylation and its relationship with systemic and oral diseases were discussed.

Key words: protein post-translational modification, glycosylation, saliva, systemic diseases, oral diseases

CLC Number:

Rui Ma, Xian Peng, Yi Xu, Dingyu Duan. Advances in salivary protein glycosylation and its relationship with systemic and oral diseases[J]. West China Journal of Stomatology, 2018, 36(3): 336-341.

References 48

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