Abstract:

Objective To investigate the effect of serum biochemistry on the development of periodontitis. Methods 225 participants without any system disease were involved in the study. Case group consist of 145 chronic peri-odontitis and was divided into gentle group （clinical attachment loss<3 mm）, moderate and severe group（clinical attachment loss≥3 mm）. Control groupconsist of 80 periodontal healthy persons. Peripheral blood sample was obtained from each subject by venipuncture. Serum chemistry variables including glucose, lipid and calcium were analyzed. SPSS 12.0 software package was adopted to analyze the investigation results. Results There’s no statistically significant difference of serum, lipid and calcium between case group and control group（P>0.05）. But case group had a higher percentage of people with abnormal glucose, lipid and calcium than control group（P<0.05）. Moderate and severe group had a significantly higher serum glucose, triglyceride and lipoproteins-cholesterol than gentle group（P<0.05）. Conclusion Abnormal level of serum glucose, lipid and calcium may increase the affectability of host to periodontitis and promote the inflammation in paradentium.

Key words: periodontitis, serum glucose, serum lipid, serum calcium