华西口腔医学杂志

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无睡眠呼吸暂停老年男性上气道及周围组织与体重和体重指数的相关性研究

郭泾1, 高雪梅2, 曾祥龙2   

  1. 1.山东大学口腔医院正畸科, 山东济南250012; 2.北京大学口腔医院正畸科, 北京100081
  • 收稿日期:2008-02-25 修回日期:2008-02-25 出版日期:2008-02-20 发布日期:2008-02-20
  • 通讯作者: 曾祥龙,Tel:010- 62179977- 2350
  • 作者简介:郭泾(1968-),女,广东人,副教授,博士

Cor r elation of upper airway and sur rounding tissues with body mass index in non- apnea aged males

GUO Jing1, GAO Xue- mei2, ZENG Xiang- long2   

  1. 1. Dept. of Orthodontics, School and Hospital of Stomatology, Shandong University, Jinan 250012, China; 2. Dept. of Orthodontics, School and Hospital of Stomatology, Peking University, Beijing 100081, China
  • Received:2008-02-25 Revised:2008-02-25 Online:2008-02-20 Published:2008-02-20
  • Contact: ZENG Xiang- long,Tel:010- 62179977- 2350

摘要:

目的探讨无睡眠呼吸暂停老年男性上气道及周围组织与体重、体重指数(BMI)的相关性。方法选择31名无睡眠呼吸暂停症状的老年男性(年龄70~84岁)为研究对象,行上气道及周围组织磁共振成像(MRI)扫描。在MRI图像上,将上气道划分为鼻咽、腭咽、舌咽和喉咽4段,测量上气道大小、形态和周围组织,对上气道及其周围组织与体重、BMI的关系进行二元变量相关分析。结果1)无睡眠呼吸暂停老年男性的鼻咽体积与体重呈负相关(P<0.05)。2)腭咽前后径最小值与体重、BMI呈正相关,腭咽前后径/左右径最大值与体重呈正相关;脂间距最小值与体重、BMI呈负相关;升支间距最小值和平均值与体重、BMI均呈正相关;脂间距/升支间距最小值与体重、BMI呈负相关;腭咽左右径/侧壁厚最小值与BMI呈负相关;以上结果均有统计学意义(P<0.05)。3)舌体积、软腭体积、脂肪垫体积、咽壁厚度与体重、BMI均无相关性(P>0.05)。结论无睡眠呼吸暂停老年男性上气道腭咽段容易受到体重和BMI的影响而发生变化。随着体重、BMI的增加,腭咽截面形状趋于圆形,腭咽受到咽旁脂肪组织的挤压作用增大。体重、BMI通过影响气道周围组织而影响腭咽形态。

关键词: 无睡眠呼吸暂停, 老年男性, 上气道及周围组织, 体重指数, 磁共振成像

Abstract:

Objective To approach the correlation of upper airway and surrounding tissues with body mass index (BMI) of non- apnea aged males. Methods Thirty- one non- apnea aged from 70 years to 84 years males(all were inspected by polysomnography and apnea hyponea index<10 times/hour) had magnetic resonance imaging scanned. In images of MRI, the upper airway was divided into four sections, including nasopharynx, velopharynx, glossopharynx and laryn - gopharynx. The sizes, forms and surrounding tissues were measured and correlation analysis of duality variable about upper airway and surrounding tissues with BMI were carried out. Results 1)The volume of nasopharynx had negative correlation with body mass(P<0.05). 2)The min anterior- posterior diameter of velopharynx had positive correlation with body mass and BMI. The max value of anterior- posterior diameter/transverse diameter of velopharynx had positive correlation with body mass. The min value of distance of fatpads had negative correlation with body mass and BMI. The min and average value of distance of ascending ramus had positive correlation with body mass and BMI. The min value of distance of fatpads/distance of ascending ramus had negative correlation with body mass and BMI. The transverse diameter/lateral velopharyngeal wall of velopharynx had positive correlation with BMI. All of above results had statistic significance(P<0.05). 3)The volume of soft palate, tongue and fatpads had no correlation with body mass and BMI(P>0.05). Conclusion The forms of sectional areas of velopharynx are subjected to body mass, and with the increasing of body mass they tend to round. In non- apnea aged males, the distance of fatpads and ascending rami have intimate relationship with body mass and BMI. The volume of soft palate, tongue, fatpads and velopharyngeal walls has little things with body mass and BMI.

Key words: non- apnea, aged males, upper airway and surrounding tissues, body mass index, magnetic resonance imaging