华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

开放面神经管的神经移植在腮腺癌手术修复中的应用

韩思源,王玉新,宋涛   

  1. 中国医科大学附属第一医院 口腔颌面外科,辽宁 沈阳110001
  • 收稿日期:2004-06-25 修回日期:2004-06-25 出版日期:2004-06-20 发布日期:2004-06-20
  • 通讯作者: 韩思源,Tel:13940422500
  • 作者简介:韩思源(1963-),男,辽宁人,主治医师,学士
  • 基金资助:
    沈阳市科委基金资助项目(200049036)

Application of Facial Canal Dissection for Recovery of Facial Nerve after Operation of Parotid Carcinoma

HANSi-yuan, WANG Yu-xin,SONG Tao   

  1. Dept. of Oral and Maxillofacial Surgery, the First Affiliated Hospital, China Medical University, Shenyang110001,China
  • Received:2004-06-25 Revised:2004-06-25 Online:2004-06-20 Published:2004-06-20

摘要:

目的 探讨侵袭到茎乳孔及周围骨质的腮腺深叶癌切除面神经后,即刻功能性修复方法的临床效果。方法 93例腮腺癌患者分为A,B,C 3组。①A组34例采用开放面神经管,去除周围骨质,将肿瘤连同腮腺及面神经扩大切除,同时行面神经移植的治疗方法;②B组35例采用未开放面神经管,仅将癌瘤连同腮腺及受累的面神经切除;③C组24例采用癌瘤与粘连的面神经干分离,保留面神经连续性的癌瘤切除。结果 A组术前有面瘫的12例患者,术后面神经功能仅2例恢复;术前无面瘫的22例患者术后有15例面神经功能恢复。术前无面瘫的患者术后面神经功能恢复率显著高于术前有面瘫的患者(P<0·05)。B组35例患者术后均造成永久性面瘫。C组24例患者,术后面神经功能均完全恢复。术前无面瘫的患者中A组患者的局部控制率和5年生存率都显著高于B组和C 组(P<0·05);术前有面瘫的患者中A组和B组的局部控制率和5年生存率无显著差异(P>0·05)。结论 开放面神经管即刻修复面神经功能的方法,既达到肿瘤切除的彻底性,又符合功能外科的发展要求,是一种比较理想的手术方法。

关键词: 面神经, 修复, 腮腺癌, 手术

Abstract:

Objective To studythe recoverymethod of facial nerve function and to compare the clinical effect after operation of parotid carcinoma, which invades stylomastoid foramen and peripheral bone in deep lobe.Methods Three operation methods were taken:①The tumor, parotid, invasive facial nerve and bone around the tumor were resected with transplatation of facial nerve.②Tumor parotid and facial nerve were resected without transplatation of facial nerve.③Tumor and parotid were dislocated from facial nerve,keeping the continuity of facial nerve.Results For the first method, facial nerve function of 68·2% patients came back to the patientswithout facial paralysis before operation, while facial nerve function of 16·7% patients came back to the patients with facial paralysis before operation. There was obvious difference between them(P<0·05).To the patients with facial paralysis before operation,the first and the second method were taken.The ratio of local control was 33·3% and 10·0% respec- tively.And survival for 5 years were 25·0% and 10·0% respectively. There was no obvious difference between the two methods (P>0·05). To the patients without facial paralysis before operation, three methods of operation were taken.The ratio of local control was 77·3%, 48·0% and 33·3% respectively. And survival for 5 years were 86·4%, 52·0% and 41·7% respectively. There was obvious difference between the firstmethod and the othertwo (P<0·05). There was no obvious difference between the second and the third methods (P>0·05).Conclusion Facial canal dissection in operation of parotid carcinomawith recovery of facial nerve can not only resect tumor completely, but also fit for development of functional surgery. It is an ideal method for surgery operation.

Key words: facial nerve, recovery, parotid carcinoma, operation