青少年局限性海绵状牙龈增生1例

doi:10.7518/hxkq.2024.2024023

华西口腔医学杂志 ›› 2024, Vol. 42 ›› Issue (5): 667-670.doi: 10.7518/hxkq.2024.2024023

青少年局限性海绵状牙龈增生1例

杨靖梅¹(), 曾昕², 吴亚菲¹, 赵寰¹()

^1.口腔疾病防治全国重点实验室国家口腔医学中心国家口腔疾病临床医学研究中心四川大学华西口腔医院牙周病科，成都 610041
^2.口腔疾病防治全国重点实验室国家口腔医学中心国家口腔疾病临床医学研究中心四川大学华西口腔医院黏膜病科，成都 610041

收稿日期:2024-01-13 修回日期:2024-04-23 出版日期:2024-10-01 发布日期:2024-09-21
通讯作者: 赵寰 E-mail:yjm881222@hotmail.com;cdzhaohuan@qq.com
作者简介:杨靖梅，主治医师，博士，E-mail：yjm881222@hotmail.com
基金资助:
四川省科技计划(2022NSFSC1521);国家自然科学基金(82170970)

Localized juvenile spongiotic gingival hyperplasia: a case report

Yang Jingmei¹(), Zeng Xin², Wu Yafei¹, Zhao Huan¹()

^1.State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Periodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
^2.State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Received:2024-01-13 Revised:2024-04-23 Online:2024-10-01 Published:2024-09-21
Contact: Zhao Huan E-mail:yjm881222@hotmail.com;cdzhaohuan@qq.com
Supported by:
Sichuan Science and Technology Program(2022NSFSC1521);National Natural Science Foundation of China(82170970)

摘要/Abstract

摘要：

青少年局限性海绵状牙龈增生（LJSGH）是一种具有独特病理表现的牙龈过度增生性疾病，其临床表现不典型，病因和发病机制尚不明确，在国内尚未有病例报道。该病的诊断主要依靠病理检测，治疗后存在复发可能性，最佳治疗方法仍缺乏一定的循证医学证据。本文报道1例LJSGH，并结合文献复习，对其临床特点、病理学特征和治疗进行总结，为该病的诊治提供参考。

关键词: 青少年局限性海绵状牙龈增生, 牙龈, 牙周手术

Abstract:

Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a kind of gingival hyperplasia with unique pathological manifestations. Its clinical manifestations are atypical, and the etiology and pathogenesis are unclear. No case report was reported in China. The diagnosis of this disease mainly relies on pathological testing, and recurrence may occur after treatment. The best treatment method still lacks medical evidence. This paper reports a case of LJSGH in a teenager and summarizes its clinical, pathological, and treatment through literature review. This work provides a reference for the diagnosis and treatment of this disease.

Key words: localized juvenile spongiotic gingival hyperplasia, gingiva, periodontal surgery

中图分类号:

R781.4

杨靖梅, 曾昕, 吴亚菲, 赵寰. 青少年局限性海绵状牙龈增生1例[J]. 华西口腔医学杂志, 2024, 42(5): 667-670.

Yang Jingmei, Zeng Xin, Wu Yafei, Zhao Huan. Localized juvenile spongiotic gingival hyperplasia: a case report[J]. West China Journal of Stomatology, 2024, 42(5): 667-670.

图/表 4

参考文献 16

1	Darling MR, Daley TD, Wilson A, et al. Juvenile spongiotic gingivitis[J]. J Periodontol, 2007, 78(7): 1235-1240.
2	Argyris PP, Nelson AC, Papanakou S, et al. Localized juvenile spongiotic gingival hyperplasia featuring unusual p16INK4A labeling and negative human papillomavirus status by polymerase chain reaction[J]. J Oral Pathol Med, 2015, 44(1): 37-44.
3	Chang JYF, Kessler HP, Wright JM. Localized juvenile spongiotic gingival hyperplasia[J]. Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 2008, 106(3): 411-418.
4	Decani S, Lodi G, Sardella A, et al. Localised juvenile spongiotic gingival hyperplasia: a case of spontaneous resolution and a literature review[J]. Eur J Paediatr Dent, 2021, 22(2): 159-162.
5	Theofilou VI, Pettas E, Georgaki M, et al. Localized juvenile spongiotic gingival hyperplasia: microscopic va-riations and proposed change to nomenclature[J]. Oral Surg Oral Med Oral Pathol Oral Radiol, 2021, 131(3): 329-338.
6	MacKenzie IC, Gao Z. Patterns of cytokeratin expression in the epithelia of inflamed human gingiva and pe-riodontal pockets[J]. J Periodontal Res, 1993, 28(1): 49-59.
7	孟焕新. 牙周病学[M]. 5版. 北京: 人民卫生出版社, 2020: 133-144.
	Meng HX. Periodontology[M]. 5th ed. Beijing: People’s Medical Publishing House, 2020: 133-144.
8	梁静, 高一珂, 张琦玥, 等. 青少年局限性海绵状牙龈增生的诊疗进展[J]. 临床口腔医学杂志, 2022, 38(3): 179-182.
	Liang J, Gao YK, Zhang QY, et al. Progress in diagnosis and treatment of localized spongiform gingival hyperplasia in adolescents[J]. J Clin Stomatol, 2022, 38(3): 179-182.
9	Allon I, Lammert KM, Iwase R, et al. Localized juvenile spongiotic gingival hyperplasia possibly originates from the junctional gingival epithelium: an immunohistoche-mical study[J]. Histopathology, 2016, 68(4): 549-555.
10	Kalogirou EM, Chatzidimitriou K, Tosios KI, et al. Localized juvenile spongiotic gingival hyperplasia: report of two cases[J]. J Clin Pediatr Dent, 2017, 41(3): 228-231.
11	Shimono M, Ishikawa T, Enokiya Y, et al. Biological characteristics of the junctional epithelium[J]. J Electron Microsc (Tokyo), 2003, 52(6): 627-639.
12	Lafuente-Ibáñez de Mendoza I, Alberdi-Navarro J, Mari-chalar-Mendia X, et al. Characterization of juvenile spon-giotic gingival hyperplasia as an entity of odontogenic origin[J]. J Periodontol, 2019, 90(12): 1490-1495.
13	Silveira HA, Toral-Rizo VH, Lara-Carrillo E, et al. Spon-giotic hyperplasia of the oral mucosa: case series and immunohistochemical analysis[J]. Oral Maxillofac Surg, 2022, 26(2): 333-337.
14	de Freitas Silva BS, Silva Sant’Ana SS, Watanabe S, et al. Multifocal red bands of the marginal gingiva[J]. Oral Surg Oral Med Oral Pathol Oral Radiol, 2015, 119(1): 3-7.
15	Nogueira VKC, Fernandes D, Navarro CM, et al. Cryotherapy for localized juvenile spongiotic gingival hyperplasia: preliminary findings on two cases[J]. Int J Paed Dentistry, 2017, 27(3): 231-235.
16	Vieira DL, Leite AF, de Souza Figueiredo PT, et al. A conservative approach for localized spongiotic gingivitis hyperplasia using photodynamic therapy: a case report and review of the literature[J]. Photobiomodul Photomed Laser Surg, 2019, 37(1): 57-61.

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青少年局限性海绵状牙龈增生1例

Localized juvenile spongiotic gingival hyperplasia: a case report

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