口腔黏膜溃疡损害出现短暂自愈的朗格汉斯细胞组织细胞增生症1例

doi:10.7518/hxkq.2023.2023084

华西口腔医学杂志 ›› 2023, Vol. 41 ›› Issue (5): 592-598.doi: 10.7518/hxkq.2023.2023084

口腔黏膜溃疡损害出现短暂自愈的朗格汉斯细胞组织细胞增生症1例

张晓玲(), 薛宁宁, 阮敏慧, 曾昕()

口腔疾病防治全国重点实验室国家口腔医学中心国家口腔疾病临床医学研究中心四川大学华西口腔医院口腔黏膜病科，成都? 610041

收稿日期:2023-03-21 修回日期:2023-05-22 出版日期:2023-10-01 发布日期:2023-10-08
通讯作者: 曾昕 E-mail:zhangxl123@stu.scu.edu.cn;zengxin22@163.com
作者简介:张晓玲，硕士， E-mail：zhangxl123@stu.scu.edu.cn
基金资助:
国家自然科学基金(U19A2005);中国医学科学院临床与转化医学研究基金(2020-I2M-C&T-A-023)

Oral mucosal lesions with transient self-healing of Langerhans cell histiocytosis: a case report

Zhang Xiaoling(), Xue Ningning, Ruan Minhui, Zeng Xin.()

State Key Laboratory of Oral Diseases & National Center for Stomatology & National Clinical Research Center for Oral Diseases & Dept. of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China

Received:2023-03-21 Revised:2023-05-22 Online:2023-10-01 Published:2023-10-08
Contact: Zeng Xin. E-mail:zhangxl123@stu.scu.edu.cn;zengxin22@163.com
Supported by:
The National Natural Science Foundation of China(U19A2005);Clinical and Translational Medicine Research Fund of Chinese Academy of Medical Sciences(2020-I2M-C&T-A-023)

摘要/Abstract

摘要：

朗格汉斯细胞组织细胞增生症（LCH）是一组原因不明的朗格汉斯细胞组织细胞异常增殖聚集疾病，多发于儿童。LCH分为勒-雪病、汉-许-克病、嗜酸性肉芽肿、先天性自愈性朗格汉斯细胞组织细胞增生症4种临床类型。病损可累及单器官或全身多处器官，临床表现根据累及器官不同而不同，皮肤黏膜可为LCH的首发部位。根据受累器官，LCH有不同的治疗方法，包括手术、放疗、联合化疗等。本文报道1例口腔黏膜溃疡性病损曾经出现短暂自愈的LCH，旨在为罕见病LCH的临床诊疗提供更多参考信息。

关键词: 朗格汉斯细胞组织细胞增生症, 自愈, 口腔黏膜溃疡, 诊断

Abstract:

Langerhans cell histiocytosis (LCH) is a group of unexplainable abnormal proliferation and aggregation of Langerhans cell. LCH can be classified into four clinical variants: Letterer-Siwe disease, Hand-Schüller-Christian disease, eosinophilic granuloma, and congenital self-healing LCH. LCH is most prevalent in children. Lesions can be localized in a single system or multiple organs, and clinical manifestations vary depending on the affected organs. The skin and mucocutaneous tissues are the starting point of the affected tissue. This study presents a LCH case characterized by transient self-healing. This case can further provide references for the clinical diagnosis and treatment of LCH.

Key words: Langerhans cell histiocytosis, self-healing, oral ulcer, diagnosis

中图分类号:

R 781.6

张晓玲, 薛宁宁, 阮敏慧, 曾昕. 口腔黏膜溃疡损害出现短暂自愈的朗格汉斯细胞组织细胞增生症1例[J]. 华西口腔医学杂志, 2023, 41(5): 592-598.

Zhang Xiaoling, Xue Ningning, Ruan Minhui, Zeng Xin.. Oral mucosal lesions with transient self-healing of Langerhans cell histiocytosis: a case report[J]. West China Journal of Stomatology, 2023, 41(5): 592-598.

图/表 6

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口腔黏膜溃疡损害出现短暂自愈的朗格汉斯细胞组织细胞增生症1例

Oral mucosal lesions with transient self-healing of Langerhans cell histiocytosis: a case report

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