以口腔溃疡为首发症状的鼻型-结外自然杀伤/T细胞淋巴瘤1例

doi:10.7518/hxkq.2022.03.017

华西口腔医学杂志 ›› 2022, Vol. 40 ›› Issue (3): 355-359.doi: 10.7518/hxkq.2022.03.017

以口腔溃疡为首发症状的鼻型-结外自然杀伤/T细胞淋巴瘤1例

穆新月¹(), 刘树泰², 孙继军³, 柳晓琳³, 李媛媛³, 王文龙³()

^1.济宁医学院附属医院口腔科，济宁 272000
^2.滨州医学院附属烟台市口腔医院牙周科，烟台 264000
^3.滨州医学院附属医院口腔科，滨州 256600

收稿日期:2021-01-11 修回日期:2022-04-10 出版日期:2022-06-01 发布日期:2022-06-01
通讯作者: 王文龙 E-mail:dentistxinyue@163.com;wwlkqwk@163.com
作者简介:穆新月，医师，硕士，E-mail：dentistxinyue@163.com
基金资助:
山东省自然科学基金(ZR2019PH075)

Nasal-type extranodal natural killer/T-cell lymphoma with oral ulcer as the earliest clinical manifestation

Mu Xinyue¹(), Liu Shutai², Sun Jijun³, Liu Xiaolin³, Li Yuanyuan³, Wang Wenlong³()

^1.Dept. of Stomatology, Affiliated Hospital of Jining Medical University, Jining 272000, China
^2.Dept. of Periodontics, Yantai Stomatological Hospital of Binzhou Medical University, Yantai 264000, China
^3.Dept. of Stomatology, Affiliated Hospital of Binzhou Medical University, Binzhou 256600, China

Received:2021-01-11 Revised:2022-04-10 Online:2022-06-01 Published:2022-06-01
Contact: Wang Wenlong E-mail:dentistxinyue@163.com;wwlkqwk@163.com
Supported by:
Natural Science Foundation of Shandong Province(ZR2019PH075);Correspondence: Wang Wenlong, E-mail: wwlkqwk@163.com

摘要/Abstract

摘要：

鼻型-结外自然杀伤/T细胞淋巴瘤（ENKTL-NT）是源于自然杀伤细胞或者细胞毒性T细胞的非霍奇金淋巴瘤的一个特殊亚型，以口腔溃疡为首发症状的情况因罕见和认识不足使其诊断具有挑战性。本文报道1例以口腔溃疡为首发症状的ENKTL-NT，并通过分析该疾病的临床病理学特征、鉴别诊断、治疗及预后、误诊原因，为临床诊治提供参考。

关键词: 鼻型-结外自然杀伤/T细胞淋巴瘤, 口腔溃疡, 诊断

Abstract:

Nasal-type extranodal natural killer/T-cell lymphoma (ENKTL-NT) is a special subtype of non-Hodgkin’s lymphoma derived from natural killer cells or cytotoxic T cells. Oral ulcers as the first symptom makes its diagnosis challenging because of its rarity and lack of understanding. We report a case of ENKTL-NT in this paper. We analyzed the clinicopathological features, differential diagnosis, treatment, prognosis and the causes of misdiagnosis to provide a diagnostic basis for dentists to make better clinical diagnosis and treatment.

Key words: nasal-type extranodal natural killer/T-cell lymphoma, oral ulcer, diagnose

中图分类号:

R 781.6

穆新月, 刘树泰, 孙继军, 柳晓琳, 李媛媛, 王文龙. 以口腔溃疡为首发症状的鼻型-结外自然杀伤/T细胞淋巴瘤1例[J]. 华西口腔医学杂志, 2022, 40(3): 355-359.

Mu Xinyue, Liu Shutai, Sun Jijun, Liu Xiaolin, Li Yuanyuan, Wang Wenlong. Nasal-type extranodal natural killer/T-cell lymphoma with oral ulcer as the earliest clinical manifestation[J]. West China Journal of Stomatology, 2022, 40(3): 355-359.

图/表 3

参考文献 18

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以口腔溃疡为首发症状的鼻型-结外自然杀伤/T细胞淋巴瘤1例

Nasal-type extranodal natural killer/T-cell lymphoma with oral ulcer as the earliest clinical manifestation

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