牙龈卟啉单胞菌在消化系统恶性肿瘤中的作用及机制

doi:10.7518/hxkq.2019.05.013

摘要/Abstract

摘要：

消化系统恶性肿瘤包括口腔癌、结直肠癌、胰腺癌、食管癌等多种疾病,是常见的高致死性恶性肿瘤。牙龈卟啉单胞菌作为牙周病最主要的致病菌,其致病性不仅仅发生在口腔,在消化系统其他部位也有不同的致病作用抑或是促进作用,其致病机制也逐渐受到研究者的重视。本文系统阐述了牙龈卟啉单胞菌在包括口腔癌的消化系统恶性肿瘤中的作用,并对其可能的致病机制进行综述。

关键词: 牙龈卟啉单胞菌, 消化系统恶性肿瘤, 致病机制

Abstract:

The malignant tumors including oral cancer, colorectal cancer, pancreatic cancer, and esophageal cancer, of the digestive system are a common high-fatal malignancy. Porphyromonas gingivalis, as the most important pathogen of periodontal disease, has been gradually proved that its invasiveness occurs not only in the mouth but also in other parts of the digestive system. Moreover, the relevant pathogenic mechanism is increasingly attracting the reseachers’ attention. In this study, the role and possible pathogenesis of Porphyromonas gingivalis in the digestive system are described in a systematic and comprehensive way.

Key words: Porphyromonas gingivalis, digestive system malignancy, pathogenic mechanism

中图分类号:

R780.2

王春萌,洪丽华,张志民,王渝. 牙龈卟啉单胞菌在消化系统恶性肿瘤中的作用及机制[J]. 华西口腔医学杂志, 2019, 37(5): 521-526.

Wang Chunmeng,Hong Lihua,Zhang Zhimin,Wang Yu. Research progress on the relationship between Porphyromonas gingivalis and the malignancy of the digestive system and possible pathogenetic mechanism[J]. West China Journal of Stomatology, 2019, 37(5): 521-526.

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