West China Journal of Stomatology

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Study of Adher ence of Normal Or al Bacter ia on Polymethyl Methyacrylate Containing Silver suppor ted Silicate Inorganic Antibacter ial

LI Gang1, 2, CHEN Zhi- qing2, WU Xing- hui3, XIAO Xiao- rong2, LI Yan- hong1, ZHU Zhu2   

  1. 1. Dept. of Stomatology, Kunming Medical College, Kunming 610093, China; 2. Key. Labo - ratory of Oral Biomedical Engineering of Ministry of Education, Sichuan University, Chengdu 610041, China; 3. College of Material Science and Technology, Yunnan University, Kunming 610091, China
  • Received:2007-06-25 Revised:2007-06-25 Online:2007-06-20 Published:2007-06-20
  • Contact: CHEN Zhi- qing,Tel:028- 85502407

Abstract:

Objective To study the oral normal bacteria adherence on polymethyl methyacrylate(PMMA)containing silver - supported silicate inorganic antibacterial, and the growth inhibitory concentration of silver - supported silicate inorganic antibacterial to normal oral bacteria were also investigated. Methods A certain volume of normal oral bacteria was inoculated on the BHI plate containing different dilution of silver- supported silicate inorganic antibacterial, then the growth of the bacteria was investigated by light microscope and biochemical methods; the oral bacteria plaque model in vitro was used to evaluate the adherence of 4 species normal oral bacteria mixture on the surface of PMMA which containing silver- supported silicate inorganic antibacterial in the proportion of 5% or 10%. Results The growth of normal oral bacteria was inhibited effectively by silver- supported silicate inorganic antibacterial within the concentration of 8%, and the growth of Porphyromonas gingivalis and Candida albicans were inhibited at concentration from 1.25% to 2.50%,but the PMMA containing silver- supported inorganic antibacterial could not prevent the adherence of bacteria within a period of 16 days. Conclusion Silver- supported silicate inorganic antibacterial has effectiveness on inhibiting the growth of normal oral bacteria,but could not prevent the adherence of oral normal bacteria mixture.

Key words: antibacterial, silver, polymethyl methyacrylate, adherence