West China Journal of Stomatology ›› 2017, Vol. 35 ›› Issue (5): 543-548.doi: 10.7518/hxkq.2017.05.019

• Orginal Article • Previous Articles     Next Articles

Research progress on QMix properties in root canal irrigation

Jiayi Wu(), Ruijie Huang()   

  1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Dept. of Pediatric Dentistry, West China Hospital of Stoma-tology, Sichuan University, Chengdu 610041, China
  • Received:2017-03-05 Revised:2017-06-02 Online:2017-10-01 Published:2017-10-01
  • Supported by:
    Sichuan University Junior Faculty Research Fund (2016SCU11042);Sichuan University Student Innovation and Entrepreneurship Training Program (1040304138012).

Abstract:

Mechanical instrumentation preparation alone is insufficient to completely remove root canal infection, and chemical irrigation is essential to eliminate infected remnants. An ideal root canal irrigant should completely remove the smear layer, lubricate the root canal, efficiently kill bacteria, induce mild or no inflammatory response in the tissues, and avoid damaging the dentin structure. However, a commercial irrigant that meets all these requirements is currently lacking. QMix is a root canal irrigation mixture of ethylenediamine tetraacetic acid (EDTA), chlorhexidine (CHX) and surfactant. This mixture can remove the smear layer efficiently, and it possesses strong antibacterial effect and good biocompatibility with minimal cytotoxicity. Furthermore, the influence of QMix on the color and micro-hardness of dentin is low, and it can improve the wettability of root canal sealant without affecting its adhesive properties. This review compares the efficiencies of QMix with other irrigants (sodium hypochlorite, CHX, EDTA, SmearClear, and MTAD) in term of smear layer removal, dentine and root canal sealing, cell cytotoxicity, and bacterial growth inhibition.

Key words: root canal irrigant, QMix, smear layer, antibacterial effect, cytotoxicity

CLC Number: