Advances in oral bacteria influencing host epigenetic regulation

doi:10.7518/hxkq.2020.05.019

Abstract

Abstract:

Epigenetics refers to a steady change in the level of gene expression caused by non-DNA sequence changes. Microbes can modulate host inflammation through epigenetic pathways to evade or expend immune responses. As an important part of human microbes, oral bacteria also have various epigenetic regulation mechanisms to affect host inflammatory responses. This article reviews the common pathways of epigenetic regulation in microbe infection and the regulation of host epigenetics by using oral microbes to provide a reference for the study of epigenetic-related mechanisms in oral diseases.

Key words: oral bacteria, epigenetics, histones modification, DNA methylation, non-coding RNA

CLC Number:

Mei Hongxiang, Chen Yilin, Shi Peilei, Yang Sirui, Xu Xin, He Jinzhi. Advances in oral bacteria influencing host epigenetic regulation[J]. West China Journal of Stomatology, 2020, 38(5): 583-588.

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