West China Journal of Stomatology ›› 2017, Vol. 35 ›› Issue (3): 328-333.doi: 10.7518/hxkq.2017.03.018

• Orginal Article • Previous Articles     Next Articles

Expression and function of microRNAs in enamel development

Yachuan Zhou(), Xuedong Zhou, Liwei. Zheng()   

  1. State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2016-08-11 Revised:2016-12-09 Online:2017-06-05 Published:2017-06-01
  • Supported by:
    Supported by: The National Natural Science Foundation of China (81470711, 81371136).

Abstract:

microRNAs (miRNAs) are endogenous short, noncoding RNAs that can negatively regulate gene expression post-transcriptionally. miRNAs are involved in multiple developmental events in various tissues and organs, including dental enamel development. Any disruption during enamel development may result in inherited enamel malformations. This article reviews the expression and function of miRNAs in enamel development.

Key words: microRNAs, enamel development, ameloblast, expression

CLC Number: