涎腺腺样囊性癌嗜神经侵袭分子机制的研究进展

doi:10.7518/hxkq.2018.02.017

摘要/Abstract

摘要：

涎腺腺样囊性癌是发生于涎腺的一种非常常见的恶性肿瘤,其重要特质是嗜神经侵袭,这一特质是其在临床手术中很难被彻底切除的重要原因之一;部分肿瘤细胞的残留易导致肿瘤术后复发,成为临床治疗的一大难题。因此,深入探讨涎腺腺样囊性癌嗜神经侵袭这一特性的分子机制对克服这一难题具有重要意义,本文就涎腺腺样囊性癌嗜神经侵袭分子机制的研究进展作一综述。

关键词: 涎腺, 腺样囊性癌, 嗜神经侵袭, 分子机制

Abstract:

Salivary adenoid cystic carcinoma is a very common malignant neoplasm in the salivary glands. One of the most important features of salivary cystic carcinoma is perineural invasion, which renders its complete removal is very difficult through clinical surgery. Consequently, tumor recurrence occurs easily after clinical surgery. Therefore, the molecular mecha-nisms of perineural invasion in salivary adenoid cystic carcinoma are necessary to explore. These mechanisms are reviewed in this paper.

Key words: salivary gland, adenoid cystic carcinoma, perineural invasion, molecular mechanism

中图分类号:

R739.87

张美, 梁新华, 汤亚玲. 涎腺腺样囊性癌嗜神经侵袭分子机制的研究进展[J]. 华西口腔医学杂志, 2018, 36(2): 204-211.

Mei Zhang, Xinhua Liang, Yaling Tang. Advances in the molecular mechanisms of perineural invasion in salivary adenoid cystic carcinoma[J]. West China Journal of Stomatology, 2018, 36(2): 204-211.

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