华西口腔医学杂志

• 基础研究 • 上一篇    下一篇

钴铬合金烤瓷冠对龈沟液中天冬氨酸转氨酶和碱性磷酸酶的影响

缪羽 刘灵军 张晓敏 李利   

  1. 内蒙古医学院第四附属医院口腔科, 内蒙古包头014030
  • 收稿日期:2010-12-25 修回日期:2010-12-25 出版日期:2010-12-20 发布日期:2010-12-20
  • 通讯作者: 李利,Tel:13337199829
  • 作者简介:缪羽(1970—),女,河北人,主任医师,硕士

Influence of cobalt-chromium alloy ceramics crown on aspartate transaminase and alkaline phosphatase of gingival crevicular fluid

MIAO Yu, LIU Ling-jun, ZHANG Xiao-min, LI Li   

  1. Dept. of Stomatology, The Fourth Affiliated Hospital of Inner Mongolia Medical College, Baotou 014030, China
  • Received:2010-12-25 Revised:2010-12-25 Online:2010-12-20 Published:2010-12-20
  • Contact: LI Li,Tel:13337199829

摘要:

目的探讨钴铬合金烤瓷冠修复后,患牙龈沟液(GCF)的质量及GCF中天冬氨酸转氨酶(AST)和碱性磷酸酶(ALP)的变化,以评价钴铬合金作为烤瓷冠内冠材料对牙周组织的影响。方法经患者知情同意,选取采用钴铬合金烤瓷冠修复并符合纳入标准的30例患者的30颗患牙,分别采集修复前、修复后1个月、修复后3个月所有修复患牙及修复前、修复后3个月对侧同名牙的GCF并称其质量,同时检测GCF内AST和ALP的水平,对不同时间的检测结果进行对比分析。结果钴铬合金烤瓷冠修复不同时间内,修复患牙GCF量、AST和ALP的差异均有统计学意义。经两两比较,GCF量和AST在3个阶段的差异均有统计学意义,术前、术后1个月、术后3个月依次升高(P<0.05);ALP术前与术后3个月比较,其差异有统计学意义(P<0.05),术后3个月高于术前。修复患牙与对侧同名牙的GCF量、AST、ALP相比较,修复术前的差异均无统计学意义(P>0.05),而术后3个月的差异均有统计学意义(P<0.05)。结论在修复术后3个月内,钴铬合金烤瓷冠可造成修复患牙的GCF量、AST和ALP的增加,在一定程度上对牙周健康有不良的影响。

关键词: 钴铬合金烤瓷冠, 龈沟液, 天冬氨酸转氨酶, 碱性磷酸酶

Abstract:

Objective The purpose of this article was to evaluate the influence of cobalt-chromium(Co-Cr) alloy as the material of inner crown on periodontal tissue through detecting the weight of diseased teeth and the concentration of aspartate transaminase(AST) and alkaline phosphatase(ALP) of the gingival crevicular fluid(GCF)after Co-Cr alloy ceramics repairing. Methods In this study, thirty cases of clinical diseased teeth were chosen from thirty patients based on patients’consent. Each tooth conformed to the inclusion criteria. All of the thirty teeth were repaired with Co -Cr alloy ceramics according to the indications. Then GCF of each diseased tooth was collected and weighed at the time of the day before prosthesis, the first and third month after repairing respectively in order to detect the concentration of AST and ALP. Furthermore, comparative analysis for different periods was performed after the data statistics. Results To the weight of GCF and the concentration of AST after the respective comparison of three indexes which was of different periods, numerous of each index increased in accordance with the rule of preoperation, postoperative first month, and postoperative third month(P<0.05). To the concentration of ALP at three time points, the compared results showed that the preoperative numerous was less than that of third month after operation and there was significant difference between them(P<0.05). To the weight of GCF and the concentration of AST and ALP, after the respective comparison of three indexes which was the diseased teeth and the contralateral teeth with the same name in the periods of pre-operation, all the differences had no statistical significance( P>0.05), but all the differences had statistical significance in the periods of postoperative third month(P< 0.05). Conclusion During the next three months after operation, GCF weight, concentration of AST and ALP of diseased teeth was gradually increased after their Co-Cr alloy ceramics crown repairing. This increase is somewhat harmful to periodontal health.

Key words: cobalt-chromium alloy ceramics crown, gingival crevicular fluid, aspartate transaminase, alkaline phosphatase