华西口腔医学杂志

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不同金属烤瓷全冠对龈沟液内可溶性细胞间黏附分子-1及白细胞介素-1β水平的影响

袁堂霞 张彦表 吴正华   

  1. 潍坊医学院口腔医学院口腔修复学教研室, 潍坊261042
  • 收稿日期:2011-10-25 修回日期:2011-10-25 出版日期:2011-10-20 发布日期:2011-10-20
  • 通讯作者: 袁堂霞,Tel:15253614196
  • 作者简介:袁堂霞(1973—),女,山东人,讲师,硕士
  • 基金资助:

    潍坊市科学技术发展计划基金资助项目(201002048)

Effect of different porcelain-fused-to-metal crown inner metal materials on the level of soluble intercellular adhesion molecule-1 and interleukin-1β in gingival crevicular fluid

Yuan Tangxia, Zhang Yanbiao, Wu Zhenghua   

  1. Dept. of Prosthodontics, School of Stomatology, Weifang Medical College, Weifang 261042, China)
  • Received:2011-10-25 Revised:2011-10-25 Online:2011-10-20 Published:2011-10-20
  • Contact: Yuan Tangxia,Tel:15253614196

摘要:

目的通过对不同内冠金属材料的烤瓷熔附金属(PFM)全冠修复后龈沟液(GCF)内可溶性细胞间黏附分子-1(sICAM-l)及白细胞介素-1β(IL-1β)水平的测定,探讨内冠金属材料对牙周组织的影响。方法将30颗牙分为镍铬合金组、钴铬合金组和金铂合金组,每组10颗,分别进行镍铬合金、钴铬合金和金铂合金PFM全冠修复。在修复前及修复后6、12个月时对受试牙进行临床检查,检测菌斑指数(PLI)、牙龈指数(GI)、龈沟探诊深度(GCD),并进行龈沟内取样,检测龈沟内GCF量和sICAM-l、IL-1β水平。结果镍铬合金组修复后6、12个月时,GI、GCD和GCF各项指标与修复前及钴铬合金组、金铂合金组相比差异均有统计学意义(P<0.05)。钴铬合金组修复后12个月时,GI、GCD和GCF指标与修复前及金铂合金组相比差异有统计学意义(P<0.05)。金铂合金组在整个实验期间其各项指标与修复前相比差异均无统计学意义(P>0.05)。结论非贵金属烤瓷全冠对牙周组织有不利影响。

关键词: 烤瓷熔附金属全冠, 龈沟液, 可溶性细胞间黏附分子-1, 白细胞介素-1β

Abstract:

Objective To investigate the effect of different inner metal materials of porcelain-fused-to-metal(PFM) crown on periodontal tissue by means of measuring the level of soluble intercellular adhesion molecule-1(sICAM-1) and interleukin-1β(IL-1β) in gingival crevicular fluid(GCF) after PFM restorations. Methods 30 teeth were divided into three groups(Ni-Cr alloy group, Co-Cr alloy group and Au-Pt alloy group, 10 teeth each group), and restored by Ni-Cr alloy, Co-Cr alloy and Au-Pt alloy PFM crown according grouping. At the point of pre-restoration, 6-month and 12- month after cementation, the clinical parameters including plaque index(PLI), gingival index(GI) and gingival crevice depth(GCD) were detected, and GCF was collected from labial and lingual of mesial site and distal site. The level of sICAM-1 and IL-1β were detected. Results At the point of 6-month and 12-month after cementation, Ni-Cr alloy group showed significant difference for GI, GCD and all GCF indexes when compared to pre-restoration, Co-Cr alloy group and Au-Pt alloy group(P<0.05). At the point of 12-month after cementation, Co-Cr alloy group showed significant difference for GI, GCD and all GCF indexes when compared to pre-restoration and Au-Pt alloy group(P<0.05). All indexes have no significant difference for Au-Pt alloy group during the 12-month experiment times when compared to pre-restoration(P>0.05). Conclusion Non-noble metal has bad effect on the periodontal tissue.

Key words: porcelain-fused-to-metal crown, gingival crevicular fluid, soluble intercellular adhesion molecule-1, interleukin-1β