华西口腔医学杂志

• 基础研究 • 上一篇    下一篇

植物乳杆菌HO-69的口腔益生性质研究

杨颖1,2,陈卫1,张灏1,汤坚1   

  1. 1.江南大学食品学院食品科学与技术国家重点实验室, 江苏无锡214122;2. 浙江省农业科学院食品加工研究所,浙江杭州310021
  • 收稿日期:2008-10-25 修回日期:2008-10-25 出版日期:2008-10-20 发布日期:2008-10-20
  • 通讯作者: 杨颖,Tel:0571-86404387
  • 作者简介:杨颖(1978-),女,山东人,助理研究员,博士

Probiotic characteristics of Lactobacillus plantarum HO-69 applied in oral cavity

YANG Ying1,2, CHEN Wei1, ZHANG Hao1, TANG Jian1   

  1. 1. State Key Laboratory of Food Science and Technology, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China; 2. Institute of Food Processing, Zhejiang Academy of Agricultural Science, Hangzhou 310021, China
  • Received:2008-10-25 Revised:2008-10-25 Online:2008-10-20 Published:2008-10-20
  • Contact: YANG Ying,Tel:0571-86404387

摘要:

目的研究植物乳杆菌HO-69在口腔中的益生性质。方法在体外模拟口腔硬组织,研究菌株对牙面与牙本质的黏附率;以MATH法确定其表面疏水性与电荷,推测菌株对口腔软组织的黏附率;以杯碟法研究其抑菌活性。结果植物乳杆菌HO-69菌株对于模拟牙面与牙本质的黏附率非常低,具有较高的表面疏水性、酸碱电荷与良好抑菌活性。结论植物乳杆菌HO-69引发龋病与促进龋病发展的概率很低,具有广谱的抑菌活性,是潜在的口腔益生菌。

关键词: 植物乳杆菌, 口腔, 黏附, 抑菌谱

Abstract:

Objective To investigate the probiotic characteristics of Lactobacillus plantarum(L.plantarum) HO-69 in oral cavity. Methods The adhesion ratios to teeth and dentine surface were determined by in vitro models. Hydrophobicity and surface charges were measured by MATH method. Inhibitory activity was measured by agar well diffusion method. Results The adhesion ratios to hard tissue were quite low. The hydrophobicity and surface charges were high, and it exhibited inhibitory activity against some pathogens. Conclusion The probability is low for L. plantarum HO-69 to initiate or accelerate dental caries. It shows broad-spectrum inhibitory activity and is potential probiotics applied in oral cavity.

Key words: Lactobacillusplantarum, oralcavity, adhesion, inhibitoryspectrum