华西口腔医学杂志

• 基础研究 • 上一篇    下一篇

经CT引导头颈部恶性肿瘤~(125)I放射性粒子的植入

张杰 张建国 宋铁砾 郑磊 黄明伟   

  1. 北京大学口腔医院颌面外科, 北京100081
  • 收稿日期:2008-02-25 修回日期:2008-02-25 出版日期:2008-02-20 发布日期:2008-02-20
  • 通讯作者: 张建国,Tel:010- 62179977- 2242
  • 作者简介:张杰(1970-),男,山西人,副主任医师,博士

CT guided inter stitial 125I seed implantation tr eatment for head and neck malignant tumor

ZHANG Jie, ZHANG Jian- guo, SONG Tie- li, ZHENG Lei, HUANG Ming- wei   

  1. Dept. of Oral and Maxillofacial Surgery, School and Hospital of Stomatology,Peking University, Beijing 100081, China
  • Received:2008-02-25 Revised:2008-02-25 Online:2008-02-20 Published:2008-02-20
  • Contact: ZHANG Jian- guo,Tel:010- 62179977- 2242

摘要:

目的探讨经CT引导125I放射性粒子植入的方法和应用。方法5例头颈部恶性肿瘤患者,3例行手术辅以125I放射性粒子植入,2例行单纯125I放射性粒子植入。按照治疗计划先行定位针植入,根据CT扫描,调整定位针的位置和方向,将125I放射性粒子依次植入靶区,即刻再次CT扫描,并验证靶区及周围重要组织器官的剂量。结果5例患者均顺利完成植入。12根定位针有5根需要进行位置和深度调整,即刻剂量验证与术前计划完全一致。结论经CT引导125I放射性粒子植入头颈部恶性肿瘤可以精确地实施治疗计划,同时可以对术后剂量进行即刻验证。

关键词: 头颈部, 恶性肿瘤, 放射性粒子

Abstract:

Objective To detect the methods and experience of CT guided interstitial 125I seed implantation treatment for head and neck malignant tumor. Methods 5 patients with head and neck malignant tumor were treated by interstitial 125I seed implantation with CT guide, 3 of them were treated with operation and adjunct seeds implantation, the other two patients were implanted seed only. According the treatment plan, register needles were punctured firstly, based on CT scan, these needle′s position and depth were adjusted, then the seeds were implanted into the target area. Another CT scan was done for the dose verification. Results The procedure of 125I seeds implantation of five patients was successful. 5 of twelve register needles were adjusted. The dose distribution of the instant verification was the same as that of treatment plan. Conclusion The CT guided seeds implantation of the head neck malignant tumors can practice the treatment plan accurately, and the dose verification can be done instantly.

Key words: head and neck, malignant tumor, radioactive seed