华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

口腔干燥症患者唾液分泌与相关因素分析

柏景坪,林  梅   

  1. 四川大学华西口腔医院  黏膜病科,四川  成都 610041
  • 收稿日期:2006-06-25 修回日期:2006-06-25 出版日期:2006-06-20 发布日期:2006-06-20
  • 通讯作者: 林 梅, Tel: 028-85503480
  • 作者简介:柏景坪(1979-), 女, 辽宁人, 博士研究生
  • 基金资助:

    国家“十五”科技攻关资助项目(2004BA720A28)

Correlation between Clinical Manifestation and Salivary Secretion of Xerostomia Patients

BAI Jing-ping, LIN Mei   

  1. Dept. of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2006-06-25 Revised:2006-06-25 Online:2006-06-20 Published:2006-06-20

摘要:

大学华西口腔医院  黏膜病科,四川  成都 610041)
[摘要]  目的  观察口腔干燥症患者的临床表现及唾液分泌情况,了解唾液分泌减少与临床表征之间的相关关系。方法  收集80例口腔干燥症患者的临床资料,并对各项指标进行量化分级,测量5 min静息唾液与刺激唾液流率,并进行相关分析。结果  80例患者中静息唾液流率下降者占75%,为口腔干燥症主要表现。静息唾液流率与口腔功能的影响程度成负相关,与患者年龄、性别、伴随症状之间无明显相关关系。结论  口腔干燥症以静息唾液分泌减少为主要表现;唾液分泌减少不是增龄性变化,且与伴随症状的出现无关。

关键词: 口腔干燥症, 静息唾液, 临床表现

Abstract:

Objective  To observe the general status, subjective syndromes, objective signs and salivary secretion of xerostomia patients for studying their correlations. Methods  Eighty patients′ clinical data were collected and classified according to certain standards. The salivary secretion including the unstimulated whole saliva(UWS) and
stimulated whole saliva(SWS) in five minutes was measured by spit method. Results  Decreased UWS was the
main presentation of xerostomia which accouted for seventy five percents. Significantly statistical correlation were found between the decreased UWS and the dry mouth signs but not the age, sex and the accompany syndromes. Conclusion  Xerostomia has a high prevalence in middle-aged women with a long course and obvious regularity. The decreased UWS is the main presentation which was not caused by physiological changes of salivary glands and has no correlation with many clinical manifestations.

Key words: xerostomia, unstimulated whole saliva, clinical manifestations