华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

淋巴闪烁显像法在口腔癌前哨淋巴结活检术中的应用

黄元丁,唐休发,李龙江   

  1. 四川大学华西口腔医院 口腔颌面外科,四川 成都610041
  • 收稿日期:2005-08-25 修回日期:2005-08-25 出版日期:2005-08-20 发布日期:2005-08-20
  • 通讯作者: 黄元丁, Tel: 13880731369
  • 作者简介:黄元丁(1979-),男,重庆人,博士研究生

Sentinel Lymphoscintigraphy in Oral Carcinoma: A Clinical Report of 10 Cases

HUANG Yuan-ding, TANG Xiu-fa, LI Long-jiang   

  1. Oral and Maxillofacial Department, West China College of Stomatology, Sichuan University, Chengdu610041, China
  • Received:2005-08-25 Revised:2005-08-25 Online:2005-08-20 Published:2005-08-20

摘要: 目的 利用淋巴闪烁显像(LS)法进行口腔癌前哨淋巴结活检术(SLNB)术前体外定位,探讨其临床应用价 值。方法 选择10例口腔癌患者,术前1 d进行LS检查,在原发灶周缘黏膜下注射核素显影剂99mTc-Dextron,进行 LS显像。术中采用染料示踪法行前哨淋巴结(SLN)定位,并行常规颈淋巴清扫术。术后对所有淋巴结进行病理学 检查。结果 10例患者中有8例于术前探查到SLN,共计10处;此8例患者术中均探测到蓝染SLN,其中8处的术 中探查结果与术前定位完全吻合。术后病理学检查此8例患者中4例淋巴结转移阳性,术前均探测到LS浓聚点。 结论 LS法术前体外定位SLN有助于SLNB在口腔癌中的应用,可作为SLNB术前的常规定位方法。

关键词: 淋巴结, 口腔癌, 淋巴闪烁显像

Abstract: Objective To determine the clinical value of preoperativein vivolocation of sentinel lymph node (SLN) by lym- phoscintigraphy (LS) in oral carcinoma.Methods 10 patients with oral carcinoma were included in this study (7 male to 3 fe- male).99m Tc-dextron was injected peritumorally 24 h before surgery. Lymphoscintigraphy imageswere obtained in anterior and lat- eral views. SLNs were detected and removed with the aid of dye during surgery. A standard radical neck dissection was then per- formed, and all lymph nodes were analyzed byHE staining.Results SLNs were successfully detected in 10 regions of 8 patients via lymphoscintigraphy. Consistent with the result of LS, 15 blue-stained SLNs were identified by means of dye method in 8 of 10 regions which the LS images indicated.Conclusion This study suggests that preoperativein vivolocation of SLN via lym- phoscintigraphy should be helpful for the application of SLNB in oral carcinoma.

Key words: lymph node, oral carcinoma, lymphoscintigraphy