下颌逐步前伸对阻塞性睡眠呼吸暂停低通气综合征患者舌咽部影响的三维有限元研究

doi:10.7518/hxkq.2013.02.009

华西口腔医学杂志

下颌逐步前伸对阻塞性睡眠呼吸暂停低通气综合征患者舌咽部影响的三维有限元研究

杨随兴1 封净2 张佐2 曲爰丽3 龚淼4 唐洁4 范俊恒4 李松青4 赵燕玲2

1.宜宾市第一人民医院口腔科，宜宾644000；2.宁夏自治区人民医院口腔科； 3.宁夏大学机械工程学院基础部，银川750021；4.宁夏医科大学口腔医学院研究生部，银川750004

出版日期:2013-04-01 发布日期:2013-04-01
通讯作者: 张佐，Tel：13895018582
作者简介:杨随兴（1983—），男，宁夏人，住院医师，硕士
基金资助:
宁夏自然科学基金资助项目（NZ-0679）；宁夏自治区科技成果转化基金资助项目（2006-12）

Three-dimensional finite element study on the change of glossopharyngeum in patient with obstructive sleep apnea hypopnea syndrome during titrated mandible advancement

Yang Suixing1, Feng Jing2, Zhang Zuo2, Qu Aili3, Gong Miao4, Tang Jie4, Fan Junheng4, Li Songqing4, Zhao Yanling2

1. Dept. of Stomatology, The First People’s Hospital of Yibin, Yibin 644000, China; 2. Dept. of Stomatology, Ningxia People，s Hospital, Yinchuan 750021, China; 3. Dept. of Basic Course, College of Mechanical Engineering, Ningxia University, Yinchuan 750021, China; 4. Postgraduate Administration Office, College of Stomatology, Ningxia Medical University, Yinchuan 750004, China

Online:2013-04-01 Published:2013-04-01

摘要/Abstract

摘要：

目的通过下颌逐步前伸对阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者舌咽部三维有限元模型进行加载，观察OSAHS患者舌咽部生物力学和形态学改变。方法对OSAHS患者上气道行薄层CT扫描，获得OSAHS患者上气道DICOM格式的图像信息，采用Mimics10.0、Imageware10.0和Ansys8.0软件建立上气道、下颌骨、舌骨及相关周围结构的三维有限元模型，然后通过逐步前伸下颌骨，观察舌咽部生物力学和形态的变化及规律。结果成功建立了OSAHS患者上气道及结构的三维有限元模型。通过逐步前伸下颌骨，舌咽部发生相应形态变化，其主要表现为：上气道舌咽部会厌尖横截面横径增加，而上气道舌咽部会厌尖横截面矢状径减小；S1主应力主要分布于上气道前壁区肌肉牵拉处，应力位置未发生明显改变，舌咽部主应力值随下颌前伸距离增加而不断增加。结论使用Mimics、Imageware和Ansys软件提高了建模效率和模型的精确性。通过对整体有限元模型的下颌逐步前伸加载，有效展示了下颌骨前伸与舌咽部两者之间的关系，研究方法可行。

关键词:

阻塞性睡眠呼吸暂停低通气综合征, 三维有限元, 生物力学

Abstract:

Objective To construct a three -dimensional finite element model of the upper airway and adjacent structure of an obstructive sleep apnea hypopnea syndrome (OSAHS) patient for biomechanical analysis. And to study the influence of glossopharyngeum of an OSAHS patient with three -dimensional finite element model during titrated mandible advancement. Methods DICOM format image information of an OSAHS patient，upper airway was obtained by thin-section CT scanning and digital image processing were utilized to construct a three-dimensional finite element model by Mimics 10.0, Imageware 10.0 and Ansys software. The changes and the law of glossopharyngeum were observed by biomechanics and morphology after loading with titrated mandible advancement. Results A three -dimensional finite element model of the adjacent upper airway structure of OSAHS was established successfully. After loading, the transverse diameter of epiglottis tip of glossopharyngeum increased significantly, although the sagittal diameter decreased correspondingly. The principal stress was mainly distributed in anterior wall of the upper airway. The location of principal stress concentration did not change significantly with the increasing of distance. The stress of glossopharyngeum increased during titrated mandible advancement. Conclusion A more precise three -dimensional finite model of upper airway and adjacent structure of an OSAHS patient is established and improved efficiency by Mimics, Image ware and Ansys software. The glossopharyngeum of finite element model of OSAHS is analyzed by titrated mandible advancement and can effectively show the relationship between mandible advancement and the glossophaiyngeum.

Key words: obstructive sleep apnea hypopnea syndrome, three-dimensional finite element, biomechanics

杨随兴封净张佐曲爰丽龚淼唐洁范俊恒李松青赵燕玲. 下颌逐步前伸对阻塞性睡眠呼吸暂停低通气综合征患者舌咽部影响的三维有限元研究[J]. 华西口腔医学杂志, doi: 10.7518/hxkq.2013.02.009.

Yang Suixing, Feng Jing, Zhang Zuo, Qu Aili, Gong Miao, Tang Jie, Fan Junheng, Li Songqing, Zhao Yanling. Three-dimensional finite element study on the change of glossopharyngeum in patient with obstructive sleep apnea hypopnea syndrome during titrated mandible advancement[J]. West China Journal of Stomatology, doi: 10.7518/hxkq.2013.02.009.

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下颌逐步前伸对阻塞性睡眠呼吸暂停低通气综合征患者舌咽部影响的三维有限元研究

Three-dimensional finite element study on the change of glossopharyngeum in patient with obstructive sleep apnea hypopnea syndrome during titrated mandible advancement

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