关键词: 人类基因组计划, 人类基因组单体型图计划, 口腔, 遗传易感性

Abstract:

The human genomic project and the international HapMap project were designed to create a genomewide database of patterns of human genetic variation, with the expectation that these patterns would be useful for genetic association studies of common diseases, thus lead to molecular diagnosis and personnel therapy. The article briefly reviewed the creation, target and achievement of those two projects. Furthermore, the authors have given four suggestions in facing to the opportunities and challenges brought by the two projects, including cultivation improvement of elites, cross binding of multi-subjects, strengthening construction of research base and initiation of natural key scientific project.

Key words: human genomic project, human genomic haplotype map project, stomatology, genetic susceptibility