West China Journal of Stomatology ›› 2019, Vol. 37 ›› Issue (1): 70-75.doi: 10.7518/hxkq.2019.01.014

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Risk factors of oral Helicobacter pylori infection among children in two kindergartens in Suzhou and the effects of oral cleaning on reducing oral Helicobacter pylori infection

Yuee Xu1,Shuxiang Li1,Xin Gao1,Xianping Wang2()   

  1. 1. Dept. of Stomatology, Suzhou Municipal Hospital, Suzhou 215002, China
    2. Dept. of Laboratory Medicine, Suzhou Municipal Hospital, Suzhou 215002, China
  • Received:2018-05-05 Revised:2018-08-12 Online:2019-02-01 Published:2019-02-01
  • Contact: Xianping Wang E-mail:523442750@qq.com


Objective This work aimed to identify the risk factors of Helicobacter pylori (H. pylori) infection in preschool children and provide effective measures for the prevention and reduction of the incidence of H. pylori infections. Methods A total of 204 children from two kindergartens in Suzhou city were recruited through a questionnaire survey. Risk factors were selected through the single factor paired data χ 2 test and multiple factor Logistic regression analysis. Oral and gastric H. pylori infections were detected by using H. pylori saliva detection (HPS) and 13C-urea breath test ( 13C-UBT). Special toothpaste for H. pylori control was selected for oral cleaning. Oral H. pylori infection rates at 2 months after special toothpaste treatment were examined by using HPS. Results The high-risk factors of H. pylori infections among preschool children included poor personal hygiene habits, such as the nibbling of fingers and the avoidance of hand-washing before meals, diet, and parent’s history of stomach disease. Among the 204 subjects enrolled in this study, 158 (77.45%), 37 (18.14%), and 28 (13.73%) were HPS positive, 13C-UBT positive, and HPS and 13C-UBT positive, respectively. The incidence of oral H. pylori infections was significantly higher than that of gastric H. pylori infections (P<0.01). The positive rate of infections significantly decreased after special toothpaste treatment (P<0.01). This result indicates that the intervention was effective. Conclusion Children must receive education on good eating habits. Individualized dining habits or the use of public chopsticks must be implemented. H. pylori infections must be detected as early as possible. Specific toothpaste for oral cleaning must be selected. These approaches could drastically prevent or reduce the incidence of H. pylori infections among preschool children.

Key words: Helicobacter pylori, preschool children, risk factors, oral health

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