华西口腔医学杂志 ›› 2020, Vol. 38 ›› Issue (3): 319-323.doi: 10.7518/hxkq.2020.03.016

• 综述 • 上一篇    下一篇

中药酚性化合物对口腔微生物调节作用的研究进展

宗雅文, 程磊, 郭强, 周学东, 任彪()   

  1. 口腔疾病研究国家重点实验室 国家口腔疾病临床医学研究中心 四川大学华西口腔医院牙体牙髓病科,成都 610041
  • 收稿日期:2019-04-21 修回日期:2019-10-19 出版日期:2020-06-01 发布日期:2020-05-28
  • 通讯作者: 任彪 E-mail:renbiao@scu.edu.cn
  • 作者简介:宗雅文,硕士,E-mail: zongywkq@foxmail.com
  • 基金资助:
    国家自然科学基金(81600858)

Research progress on the regulation of phenolic compounds of traditional Chinese herbs on oral microbes

Zong Yawen, Cheng Lei, Guo Qiang, Zhou Xuedong, Ren Biao()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2019-04-21 Revised:2019-10-19 Online:2020-06-01 Published:2020-05-28
  • Contact: Biao Ren E-mail:renbiao@scu.edu.cn
  • Supported by:
    The National Natural Science Foundation of China(81600858)

摘要:

酚性化合物广泛存在于天然中药植物中,具有抗氧化、抗炎等药理特性,是许多中药发挥药理作用的主要成分。口腔微生物的组成、代谢等关系着口腔微生态的平衡,是口腔疾病发生、发展的关键因素。近来的研究发现,中药酚性化合物可以调节口腔微生物组成、代谢及致病毒力等,从而在龋病、牙周病、口腔黏膜感染等口腔疾病的防治领域发挥着重要作用。本文就中药酚性化合物对口腔微生物的调节作用作一综述。

关键词: 中药, 酚性化合物, 口腔微生物, 致病毒力

Abstract:

Phenolic compounds are widely found in natural Chinese medicinal plants and have excellent pharmacological properties, such as antioxidation and anti-inflammation. They are the main pharmacological components of many medicinal Chinese herbs. Oral microbiota, especially its composition and metabolism, is highly related to the balance of oral microecology and plays a key role in the occurrence and development of oral diseases. Recent studies have shown that phenolic compounds of traditional Chinese herbs can prevent and treat oral diseases, such as caries, periodontal disease, and oral mucosal infection, by regulating the composition, metabolites, and virulence of oral microorganisms. This review will summarize and discuss the regulation of phenolic compounds on oral microbes.

Key words: traditional Chinese herbs, phenolic compounds, oral microbes, pathogenic virulence

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