West China Journal of Stomatology ›› 2023, Vol. 41 ›› Issue (1): 1-10.doi: 10.7518/hxkq.2023.01.001

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Progress of research on oral mucosal adhesive agents

Zhao Hang.()   

  1. State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Preclinical Stomatology, West China School of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2022-09-06 Revised:2022-12-28 Online:2023-02-01 Published:2023-02-21
  • Contact: Zhao Hang. E-mail:zhaohangahy@scu.edu.cn
  • Supported by:
    The National Natural Science Foundations of China(81922020);The Sichuan Provincial Department of Science and Technology(2021-YJ-2021)

Abstract:

Oral mucosal administration is extensively used to treat systemic diseases and oral mucosal diseases owing to unique oral mucosal structure and convenient administration. However, the special microenvironment of the oral cavity being open, moving, and humid causes oral mucosal drug delivery to face great challenges. To address this dilemma, local adhesive agents have been widely studied for sustained drug delivery and improved bioavailability, showing broad prospects. Recently, the author has performed studies on oral mucosal adhesive agents. In this paper, the progress of research on oral mucosal adhesive materials is reviewed.

Key words: oral mucosa, local administration, adhesion

CLC Number: