Relationship between oral and gut microbes

doi:10.7518/hxkq.2017.03.017

Abstract

Abstract:

Oral cavity?and gut are important parts of the human digestive tract. The structure and pathogenesis of oral and gut microbial communities have been extensively investigated. The interaction and pathogenic effects of oral and gut micro-biota have also been widely explored. This review aimed to integrate data from literature and discuss the structures and func-tions of microbial communities in the oral cavity and gut. The mutual colonization and pathogenesis of oral and gut microbes and the relationship between these phenomena and involved systemic diseases are also described.

Key words: oral cavity, gut, microbiome, systemic diseases

CLC Number:

R 780.2

Xingqun Cheng, Xin Xu, Xuedong. Zhou. Relationship between oral and gut microbes[J]. West China Journal of Stomatology, 2017, 35(3): 322-327.

References 53

[1]	Lederberg J, McCray A. The Scientist: ‘Ome Sweet ’ Omics—a genealogical treasury of words[J]. The Scientist, 2001, 15(7):22-27.
[2]	Peterson J, Garges S, Giovanni M, et al.The NIH human microbiome project[J]. Genome Res, 2009, 19(12):2317-2323.
[3]	Methé BA, Nelson KE, Pop M, et al.A framework for human microbiome research[J]. Nature, 2012, 486(7402):215-221.
[4]	Huttenhower C, Gevers D, Knight R, et al.Structure, func-tion and diversity of the healthy human microbiome[J]. Na-ture, 2012, 486(7402):207-214.
[5]	Gevers D, Knight R, Petrosino JF, et al.The Human Micro-biome Project: a community resource for the healthy human microbiome[J]. PLoS Biol, 2012, 10(8):e1001377.
[6]	Costello EK, Stagaman K, Dethlefsen L, et al.The applica-tion of ecological theory toward an understanding of the human microbiome[J]. Science, 2012, 336(6086):1255-1262.
[7]	Marshall BJ, Warren JR.Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration[J]. Lancet, 1984, 1(8390):1311-1315.
[8]	Krajden S, Fuksa M, Anderson J, et al.Examination of hu-man stomach biopsies, saliva, and dental plaque for Campy-lobacter pylori[J]. J Clin Microbiol, 1989, 27(6):1397-1398.
[9]	Nisha KJ, Nandakumar K, Shenoy KT, et al.Periodontal disease and Helicobacter pylori infection: a community-based study using serology and rapid urease test[J]. J In-vestig Clin Dent, 2016, 7(1):37-45.
[10]	Bharath T, Reddy M, Dhanapal R, et al.Molecular detection and correlation of Helicobacter pylori in dental plaque and gastric biopsies of dyspeptic patients[J]. J Oral Maxillofac Pathol, 2014, 18(1):19-24.
[11]	Chaudhry S, Khan A, Butt A.Helicobacter pylori in dental plaque; Is it related to brushing frequency, plaque load and oral health status[J]. J Coll Physicians Surg Pak, 2011, 21(10):589-592.
[12]	郭瑞, 车团结, 居军, 等. 兰州地区幽门螺杆菌感染状况分析[J]. 华西口腔医学杂志, 2014, 31(4):358-362.
	Guo R, Che TJ, Ju J, et al.Analysis of the infection status of saliva Helicobacter pylori in Lanzhou[J]. West Chin J Stomatol, 2014, 31(4):358-362.
[13]	杨凯毓, 李雨庆, 周学东. 口腔幽门螺杆菌与胃幽门螺杆菌感染关系的研究进展[J]. 华西口腔医学杂志, 2014, 32(3):314-318.
	Yang KY, Li YQ, Zhou XD.Overview of researches for Helicobacter pylori in oral cavity and stomach[J]. West Chin J Stomatol, 2014, 32(3):314-318.
[14]	Adler I, Muiño A, Aguas S, et al.Helicobacter pylori and oral pathology: relationship with the gastric infection[J]. World J Gastroenterol, 2014, 20(29):9922-9935.
[15]	Vahedi M, Khalilian A, Abdollahzadeh S, et al.Saliva secre-tion and efficacy of Helicobacter pylori eradication in peptic ulcer patients[J]. J Dent, 2011, 8(4):165-169.
[16]	Pushalkar S, Mane SP, Ji X, et al.Microbial diversity in saliva of oral squamous cell carcinoma[J]. FEMS Immunol Med Microbiol, 2011, 61(3):269-277.
[17]	Lalla E, Papapanou PN.Diabetes mellitus and periodontitis: a tale of two common interrelated diseases[J]. Nat Rev En-docrinol, 2011, 7(21):738-748.
[18]	Zhang X, Zhang D, Jia H, et al.The oral and gut microbio-mes are perturbed in rheumatoid arthritis and partly norma-lized after treatment[J]. Nat Med, 2015, 21(8):895-905.
[19]	Xu X, He J, Xue J, et al.Oral cavity contains distinct niches with dynamic communities[J]. Environ Microbiol, 2015, 17(3):699-710.
[20]	Dewhirst FE, Izard J, Paster BJ, et al..
[21]	Frank DN, St Amand AL, Feldman RA, et al.Molecular-phylogenetic characterization of microbial community im-balances in human inflammatory bowel diseases[J]. Proc Natl Acad Sci U S A, 2007, 104(34):13780-13785.
[22]	Clemente JC, Ursell LK, Parfrey LW, et al.The impact of the gut microbiota on human health: an integrative view[J]. Cell, 2012, 148(6):1258-1270.
[23]	Jandhyala SM, Talukdar R, Subramanyam C, et al.Role of the normal gut microbiota[J]. World J Gastroenterol, 2015, 21(29):8787-8803.
[24]	Schloissnig S, Arumugam M, Sunagawa S, et al.Genomic variation landscape of the human gut microbiome[J]. Nature, 2013, 493(7430):45-50.
[25]	Said HS, Suda W, Nakagome S, et al.Dysbiosis of salivary microbiota in inflammatory bowel disease and its association with oral immunological biomarkers[J]. DNA Res, 2014, 21(1):15-25.
[26]	Spor A, Koren O, Ley R.Unravelling the effects of the en-vironment and host genotype on the gut microbiome[J]. Nat Rev Microbiol, 2011, 9(4):279-290.
[27]	Hur KY, Lee MS.Gut microbiota and metabolic disorders[J]. Diabetes Metab J, 2015, 39(3):198-203.
[28]	Nakajima M, Arimatsu K, Kato T, et al.Oral administra-tion of P. gingivalis induces dysbiosis of gut microbiota and impaired barrier function leading to dissemination of Entero-bacteria to the liver[J]. PLoS One, 2015, 10(7):e0134234.
[29]	Qin N, Yang F, Li A, et al.Alterations of the human gut microbiome in liver cirrhosis[J]. Nature, 2014, 513(7516):59-64.
[30]	Bashir A, Miskeen AY, Bhat A, et al.Fusobacterium nuc-leatum: an emerging bug in colorectal tumorigenesis[J]. Eur J Cancer Prev, 2015, 24(5):373-385.
[31]	Mima K, Nishihara R, Qian ZR.Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis[J]. Gut, 2016, 65(12):1973-1980.
[32]	Guinane CM, Tadrous A, Fouhy F, et al.Microbial compo-sition of human appendices from patients following appen-dectomy[J]. MBio, 2013, 4(1):e00366-12.
[33]	Zhong D, Brower-Sinning R, Firek B, et al.Acute appen-dicitis in children is associated with an abundance of bac-teria from the phylum Fusobacteria[J]. J Pediatr Surg, 2014, 49(3):441-446.
[34]	Couvigny B, de Wouters T, Kaci G, et al. Commensal Strep-tococcus salivarius modulates PPARγ transcriptional activity in human intestinal epithelial cells[J]. PLoS One, 2015, 10(5):e0125371.
[35]	Zhang Z, Zhai H, Geng J, et al.Large-scale survey of gut microbiota associated with MHE via 16S rRNA-based pyro-sequencing[J]. Am J Gastroenterol, 2013, 108(10):1601-1611.
[36]	Sugita R, Hata E, Miki A, et al.Gut colonization by Candida albicans inhibits the induction of humoral immune tolerance to dietary antigen in BALB/c mice[J]. Biosci Microbiota Food Health, 2012, 31(4):77-84.
[37]	Singhal S, Dian D, Keshavarzian A, et al.The role of oral hygiene in inflammatory bowel disease[J]. Dig Dis Sci, 2011, 56(1):170-175.
[38]	He X, McLean JS, Guo L, et al. The social structure of mi-crobial community involved in colonization resistance[J]. ISME J, 2014, 8(3):564-574.
[39]	Ordovas JM, Mooser V.Metagenomics: the role of the mi-crobiome in cardiovascular diseases[J]. Curr Opin Lipidol, 2006, 17(2):157-161.
[40]	Armingohar Z, Jørgensen JJ, Kristoffersen AK, et al. Bac-teria and bacterial DNA in atherosclerotic plaque and aneurys-mal wall biopsies from patients with and without periodon-titis[J/OL]. J Oral Microbiol, 2014-05-15. doi: 10.3402/jom.v6.23408.
[41]	Hansson GK.Inflammation, atherosclerosis, and coronary artery disease[J]. N Engl J Med, 2005, 352(16):1685-1695.
[42]	Haraszthy VI, Zambon JJ, Trevisan M, et al.Identification of periodontal pathogens in atheromatous plaques[J]. J Perio-dontol, 2000, 71(10):1554-1560.
[43]	Koren O, Spor A, Felin J, et al.Human oral, gut, and plaque microbiota in patients with atherosclerosis[J]. Proc Natl Acad Sci U S A, 2011, 108(Suppl 1):4592-4598.
[44]	McInnes IB, Schett G. Thepathogenesis of rheumatoid ar-thritis[J]. New Engl J Med, 2011, 365(23):2205-2219.
[45]	Brusca SB, Abramson SB, Scher JU.Microbiome and mu-cosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity[J]. Curr Opin Rheumatol, 2014, 26(1):101-107.
[46]	Chen Y, Yang F, Lu H, et al.Characterization of fecal mi-crobial communities in patients with liver cirrhosis[J]. Hepa-tology, 2011, 54(2):562-572.
[47]	Patel VC, Shawcross DL.Salivary microbiota-immune pro-filing in cirrhosis: could this be the noninvasive strategy that will revolutionize prognostication in hepatology[J]. Hepato-logy, 2015, 62(4):1001-1003.
[48]	Bajaj JS, Betrapally NS, Hylemon PB, et al.Salivary micro-biota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy[J]. Hepatology, 2015, 62(4):1260-1271.
[49]	Mackenzie DA, McLay K, Roos S, et al. Draft genome se-quence of a novel Lactobacillus salivarius strain isolated from piglet[J/OL]. Genome Announc, 2014-02-13. doi: 10.1128/genomeA.01231-13.
[50]	Zhang M, Wang F, Jiang L, et al.Lactobacillus salivarius REN inhibits rat oral cancer induced by 4-nitroquioline 1-oxide[J]. Cancer Prev Res (Phila), 2013, 6(7):686-694.
[51]	Zhang M, Fan X, Fang B, et al.Effects of Lactobacillus sali-varius Ren on cancer prevention and intestinal microbiota in 1, 2-dimethylhydrazine-induced rat model[J]. J Microbiol, 2015, 53(6):398-405.
[52]	Szymula A, Rosenthal J, Szczerba BM, et al.T cell epitope mimicry between Sjögren’s syndrome antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria[J]. Clin Im-munol, 2014, 152(1/2):1-9.
[53]	Saxena D, Li Y, Yang L, et al.Human microbiome and HIV/AIDS[J]. Curr HIV/AIDS Rep, 2012, 9(1):44-51.