Evaluation of the clinical effect of concentrated growth factor combined with sticky bone in maxillary anterior alveolar ridge preservation

doi:10.7518/hxkq.2025.2025013

Abstract

Abstract:

Objective To compare the clinical effects of concentrated growth factor (CGF) membrane and Bio-Gide^® collagen membrane, combined with Bio-Oss^® sticky bone respectively in alveolar ridge preservation (ARP) of maxillary anterior teeth. Methods Thirty patients who needed alveolar ridge preservation after maxillary anterior tooth extraction were selected and randomly assigned to the Bio-Gide group and the CGF group. In both groups, the extraction sockets were tightly filled with the Bio-Oss^® sticky bone. In the Bio-Gide group used Bio-Gide^® collagen membrane to cover the upper edge of the Bio-Oss^® sticky bone and closed the wound. The CGF group, the CGF membrane was covered on the upper edge of the Bio-Oss^® sticky bone and the wound was closed. The soft tissue wound healing status at 10 days after ARP, the changes in alveolar ridge height and width immediately after ARP and at 6 months after ARP, and the doctor-patient satisfaction at 6 months after ARP were compared and evaluated between the two groups. Results At 6 months after ARP, there was no statistically significant difference in the changes of alveolar bone width and height between the two groups (P>0.05). However, the CGF group showed better performance in soft tissue healing after ARP and doctor-patient satisfaction, and the differences were statistically significant (P<0.05). Conclusion Compared with the Bio-Gide^® collagen membrane, the combined application of CGF membrane and Bio-Oss^® sticky bone can lead to better soft tissue healing after ARP of maxillary anterior teeth and higher doctor-patient satisfaction, showing obvious advantages in ARP of maxillary anterior teeth.

Key words: alveolar ridge preservation, sticky bone, concentrated growth factor, collagen membrane, implant

CLC Number:

R783.4

Wei Xueqin, Zhang Shengzhi, Ba Kai. Evaluation of the clinical effect of concentrated growth factor combined with sticky bone in maxillary anterior alveolar ridge preservation[J]. West China Journal of Stomatology, 2025, 43(5): 671-678.

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组别	W₀	W₁	W_Δ
P值	0.46	0.67	0.31
Bio-Gide组	7.52±1.29	6.17±1.08	1.35±0.63
CGF组	7.81±1.52	6.25±1.49	1.56±0.92

组别	H₀	H₁	H_Δ
P值	0.82	0.98	0.52
Bio-Gide组	18.51±2.17	17.29±1.76	1.22±0.78
CGF组	18.73±1.84	17.46±1.53	1.27±0.69

组别	创面愈合评分				P值
组别	0分	1分	2分	3分	P值
Bio-Gide组	5	7	4	0	0.04
CGF组	8	5	1	0	0.04

组别	患者	医生
P值	0.008	0.031
Bio-Gide组	7（6，8）	8（7，8）
CGF组	9（9，9）	9（8，9）