Oral health status of patients undergoing hemodialysis: a Meta-analysis

doi:10.7518/hxkq.2017.02.009

Abstract

Abstract:

Objective This study aimed to systematically evaluate the oral health status of patients suffering from chronic renal failure and undergoing hemodialysis (HD). Methods Electronic databases, namely, China National Knowledge Infras-tructure, Wanfang Data base, PubMed, Web of Science, and Cochrane Library, were searched until May 2016 for cross-sectional and case-control studies that investigated the oral health status of patients suffering from chronic renal failure and undergoing HD. Two reviewers independently screened the trials, extracted the data, assessed the quality, and conducted a Meta-analysis with RevMan 5.3 in accordance with the inclusion and exclusion criteria. Results Sixteen studies satisfied the eligibility criteria. Meta-analysis revealed that plaque index (MD=0.62, 95%CI: 0.51-0.72), calculus index (MD=1.09, 95%CI: 0.56-1.63), probing depth (MD=0.63, 95%CI: 0.29-0.98), and attachment loss (MD=0.63, 95%CI: 0.56-0.69) were significantly higher in the patients undergoing HD than in the healthy control group (P<0.01). No significant differences in decayed missing filled teeth (MD=1.12, 95%CI: -1.08-3.32) were observed between the patients undergoing HD and the healthy control group (P=0.32). Conclusion The prevalence of caries in patients undergoing HD is similar to that in the healthy control group. However, these patients are at a higher risk of acquiring periodontal diseases than the healthy control group. Thus, the oral health status of these patients should be further evaluated in clinical treatments.

Key words: hemodialysis, renal failure, periodontal disease, caries, Meta-analysis

CLC Number:

R780.1

Xi Wei, Bo Hu, Haiyang Peng, Chang Liu, Jinlin Song, Ming Tang. Oral health status of patients undergoing hemodialysis: a Meta-analysis[J]. West China Journal of Stomatology, 2017, 35(2): 155-161.

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作者	年份	国家	研究类型	平均年龄/岁		透析时间/月	性别（男/女）
作者	年份	国家	研究类型	HD组	对照组	透析时间/月	HD组	对照组
Chhokra M^[6]	2013	印度	横断面研究	38.03±7.41	40.55+5.45	未提及	13/27	14/26
Castillo A^[7]	2007	西班牙	横断面研究	61.5±18.04	58.9±18.7	43.4±38.96	24/28	24/28
王立飞^[9]	2003	中国	病例对照研究	未提及	未提及	未提及	33/14	20/15
房付春^[10]	2013	中国	病例对照研究	53.28±9.54	53.48±8.58	47.71±50.67	71/59	71/59
Chamani G^[11]	2009	伊朗	横断面研究	53.12±16.73	45.17±12.02	未提及	42/26	17/13
刘涛^[12]	2015	中国	病例对照研究	58.4±11.7	58.4±11.7	49.2±43.2	41/44	41/44
Tiwari V^[13]	2013	印度	病例对照研究	未提及	未提及	未提及	28/2	28/2
Torres SA^[14]	2009	巴西	病例对照研究	41.7±7.2	41.7±7.2	29±22	12/4	10/4
Bayraktar G^[15]	2008	土耳其	病例对照研究	46±15	46±18	39±25	23/18	22/39
Marakoglu I^[16]	2003	土耳其	病例对照研究	50.4±14.2	50.2±12.4	未提及	20/16	20/16
Pakpour AH^[17]	2015	伊朗	病例对照研究	57.7±17.01	55.8±15.9	52.12±29.86	322/190	158/97
Cengiz MI^[18]	2009	土耳其	病例对照研究	47.85±14.61	44.80±10.22	未提及	37?31	21?20
Gavaldá C^[19]	1999	英国	病例对照研究	58.9±14.9	55.7±10.7	59.8±43.9	53/52	29/24
Bots CP^[20]	2006	荷兰	横断面研究	42.6±9.2	41.3±8.4	28.6±16.9	30/12	326/482
Bayraktar G^[21]	2009	土耳其	横断面研究	46±14	45±18	27±21	56/44	46/65
Davidovich E^[22]	2005	美国	病例对照研究	14.3±1.11	12.6±1.04	未提及	14/8	15/23
Tadakamadla J^[23]	2014	印度	病例对照研究	46.27±1.42	43.14±2.31	未提及	未提及	未提及

文献	①	②	③	④	⑤-A	⑤-B	⑥	⑦	⑧	NOS总分
Chhokra M 2013^[6]	0	0	1	1	1	1	1	1	1	7
Castillo A 2007^[7]	1	0	1	1	1	1	1	1	1	8
房付春2013^[10]	1	1	1	1	1	0	1	1	1	8
Chamani G 2009^[11]	1	1	1	1	1	0	1	1	1	8
刘涛 2015^[12]	1	1	1	1	1	0	1	1	1	8
Tiwari V 2013^[13]	1	1	1	1	1	0	1	1	1	8
Torres SA 2010^[14]	1	0	1	1	1	0	1	1	1	7
Bayraktar G 2008^[15]	1	1	1	1	1	0	1	1	1	8
Marakoglu I 2003^[16]	0	0	1	1	1	0	1	1	1	6
Pakpour AH 2015^[17]	1	1	1	1	1	0	1	1	1	8
Cengiz MI 2009^[18]	0	0	1	1	1	1	1	1	1	7
Gavaldá C 1999^[19]	0	0	1	1	1	1	1	1	1	7
Bots CP 2006^[20]	1	1	1	0	1	0	1	1	1	7
Bayraktar G 2009^[21]	1	1	1	0	1	1	1	1	1	8
Davidovich E 2005^[22]	1	1	0	1	1	0	1	1	1	7
Tadakamadla J 2014^[23]	0	1	0	1	1	0	1	1	1	6