华西口腔医学杂志 ›› 2012, Vol. 30 ›› Issue (5): 539-543.doi: 10.3969/j.issn.1000-1182.2012.05.021

• 专栏论著 • 上一篇    下一篇

萎缩性舌炎患者舌背菌群及相关因素的研究

聂艳萍1,2 刘静1 彭骊苏1 林梅3 肖丽英1   

  1. 1.口腔疾病研究国家重点实验室, 四川大学, 成都610041; 2.山西红十字口腔医院牙周科, 太原030001;3.四川大学华西口腔医院黏膜病科, 成都610041
  • 收稿日期:2011-08-30 修回日期:2012-05-21 出版日期:2012-10-01 发布日期:2012-10-01
  • 通讯作者: 林梅,Tel:028-85503480
  • 作者简介:聂艳萍(1973—),女,山西人,副主任医师,硕士
  • 基金资助:

    国家十五科技攻关计划基金资助项目(2004BA720A28)

Research on flora on tongue dorsum of patients with atrophic glossitis and correlated factors

Nie Yanping1,2, Liu Jing1, Peng Lisu1, Lin Mei3, Xiao Liying1.   

  1. 1. State Key Laboratory of Oral Diseases, Sichuan University, Chengdu 610041, China; 2. Dept. of Periodontology, Shanxi Red Cross Stomatological Hospital, Taiyuan 030001, China; 3. Dept. of Oral Medicine, West China School of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2011-08-30 Revised:2012-05-21 Online:2012-10-01 Published:2012-10-01

摘要:

目的对老年萎缩性舌炎患者的舌背细菌及相关因素进行研究,探讨舌背菌群在萎缩性舌炎状况下的变化,为临床研究和治疗提供思路。方法收集60例萎缩性舌炎患者和40例正常对照志愿者,检查两组的一般情况、口腔健康状况、唾液流量及pH值,采集舌背菌群样本进行分离、培养和鉴定,对结果进行统计学分析。结果1)舌炎组以疼痛、口干、味觉障碍为主要症状,女性患者占75.00%。2)舌炎组中,系统性疾病以胃炎、冠心病、贫血较多见。3)与对照组相比,舌炎组的口腔卫生状况较差,唾液流速和pH值均较低。4)舌炎组与对照组、伴有不同系统性疾病的舌炎患者与对照组、完全型与局限型舌炎患者相比,舌背某些细菌(如血链球菌、口腔球菌、金黄色葡萄球菌、假丝酵母菌等)的菌落数量和检出率均有一定的差异。结论萎缩性舌炎是宿主、口腔环境、微生物三方面共同作用的结果;虽然舌背菌群的改变与萎缩性舌炎之间的具体关系尚无定论,但舌背菌群的改变与疾病的发生、发展有联系。

关键词: 萎缩性舌炎, 舌背, 菌落

Abstract:

Objective To examine the flora samples from the tongue dorsum of the atrophic glossitis group and to discuss the relationship so as to provide a thinking pattern for therapy and a clue for deeper research. Methods To collect personal information on 60 cases of atrophic glossitis and 40 cases of volunteers as control. The main items include general status, oral examination, salivary flow rate, pH value and bacteria test. All data were analyzed statistically. Results 1)Among the 60 cases, 75.00% were female patients. Glosso-pain, dry mouth and taste loss were the most common symptoms. 2)In regard to the pathogenic factors, the systematic diseases were often visible, i.e. gastritis, coronary disease and anemia. 3)Oral hygiene of the patients was worse than that of the control group, the saliva flow rate and pH value were lower than that of the control. 4)The statistic analysis showed that the quantity of some bacteria of tongue dorsum and their detectable rate were different between the glossitis group and the control one, between the patients with atrophic glossitis who also suffered from different systematic diseases and the control group, and between the complete type and the partial type. These bacteria included Streptococcus sanguis, Stomatococcus,
Staphylococcus aureus, Saccharomyces, etc. Conclusion Atrophic glossitis is the consequence co-affected by host, circumstances of oral cavity and bacteria. The tangible relationship between atrophic glossitis and micro-ecological changes on glossal dorsum has not been confirmed yet, however, flora change on dorsum may have relations with occurrence, and development of the disease.