华西口腔医学杂志

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口腔颌面部肿瘤综合治疗设计中的平衡理念

杨湛   

  1. 云南省第三人民医院口腔颌面外科, 云南昆明650011
  • 收稿日期:2008-02-25 修回日期:2008-02-25 出版日期:2008-02-20 发布日期:2008-02-20
  • 通讯作者: 杨湛,Tel:13708738809
  • 作者简介:杨湛(1964-),男,江苏人,教授,博士

Balancing ther apeutic idea in the tr eatment plan of or al maxillofacial neoplasm

YANG Zhan   

  1. Dept. of Oral and Maxillofacial Surgery, The Third People′s Hospital of Yunnan Province, Kunming 650011, China
  • Received:2008-02-25 Revised:2008-02-25 Online:2008-02-20 Published:2008-02-20
  • Contact: YANG Zhan,Tel:13708738809

摘要:

本文在重点回顾口腔颌面部肿瘤发病情况、影响治疗的主要生物学和病理学因素、综合治疗现状和进展的基础上,提出在肿瘤的综合治疗设计中,应在客观承认肿瘤生物学治愈缺乏可靠依据、肿瘤生物学转移是必然规律、机体存在着自身平衡调节系统的前提下,确立以最大限度地保证患者生存质量、延长患者生存期和减少患者身心痛苦为目标的妥协性平衡治疗方案,使治疗不过度损害患者的正常生理功能,使治疗后残存的肿瘤细胞能在免疫监测下与荷瘤机体和平共处,而使肿瘤真正成为一种慢性疾病,使肿瘤治疗成为一种不因医源性原因危及治疗对象安全的平和治疗。

关键词: 口腔颌面部肿瘤, 平衡治疗, 治疗计划

Abstract:

According to the reviews of some critical factors, such as incidence rate of oral maxillofacial neoplasm, influence factors of molecular- biology and pathology, and advancement of comprehensive treatments, a new treatment idea- balancing therapeutic idea(BTI)has been put forward to improve the patients′life quality, prolong their survival, and decrease their psychological and physiological pains. The key point of the BTI is that the doctors should pay much attention to the patients′overall benefit and keep away from the risk of over- treatment based on the fact that it is impossible that cancer cells are killed out at the biological level. It is important for doctors to let the residual tumor cells be monitored and restricted with body′s immune defense system under the condition of normal physiological function and not being destroyed by improper treatment. This is the most important purpose of BTI that let oral cancer become chronic disease authentically and improve the therapeutic safety and efficiency.

Key words: oral maxillofacial neoplasm, balancing therapeutic idea, treatment plan