关键词: 抗菌剂, 银, 聚甲基丙烯酸树脂, 黏附

Abstract:

Objective To study the oral normal bacteria adherence on polymethyl methyacrylate（PMMA）containing silver - supported silicate inorganic antibacterial, and the growth inhibitory concentration of silver - supported silicate inorganic antibacterial to normal oral bacteria were also investigated. Methods A certain volume of normal oral bacteria was inoculated on the BHI plate containing different dilution of silver- supported silicate inorganic antibacterial, then the growth of the bacteria was investigated by light microscope and biochemical methods; the oral bacteria plaque model in vitro was used to evaluate the adherence of 4 species normal oral bacteria mixture on the surface of PMMA which containing silver- supported silicate inorganic antibacterial in the proportion of 5% or 10%. Results The growth of normal oral bacteria was inhibited effectively by silver- supported silicate inorganic antibacterial within the concentration of 8%, and the growth of Porphyromonas gingivalis and Candida albicans were inhibited at concentration from 1.25% to 2.50%，but the PMMA containing silver- supported inorganic antibacterial could not prevent the adherence of bacteria within a period of 16 days. Conclusion Silver- supported silicate inorganic antibacterial has effectiveness on inhibiting the growth of normal oral bacteria，but could not prevent the adherence of oral normal bacteria mixture.

Key words: antibacterial, silver, polymethyl methyacrylate, adherence