华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

30例舌下腺恶性肿瘤临床病理分析

于涛;高庆红;王晓毅;温玉明;王昌美;张勇   

  1. 四川大学华西口腔医院头颈肿瘤外科, 四川成都610041
  • 收稿日期:2007-02-25 修回日期:2007-02-25 出版日期:2007-02-20 发布日期:2007-02-20
  • 通讯作者: 温玉明,Tel:028- 85501447
  • 作者简介:于涛(1981-),男,山东人,硕士研究生

A Retrospective Clinicopathologic Study of 30 Cases of Sublingual Gland Malignant Tumor s

YU Tao, GAO Qing- hong, WANG Xiao- yi, WEN Yu- ming, WANG Chang- mei, ZHANG Yong   

  1. Dept. of Head and Neck Oncology Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, China
  • Received:2007-02-25 Revised:2007-02-25 Online:2007-02-20 Published:2007-02-20
  • Contact: WEN Yu- ming,Tel:028- 85501447

摘要:

目的探讨舌下腺恶性肿瘤的临床病理特征及治疗方法。方法对1955—2005年四川大学华西口腔医院颌面外科收治的30例舌下腺恶性肿瘤患者进行回顾性分析。结果30例舌下腺恶性肿瘤患者中,男性18例,女性12例;平均年龄50.6岁。腺样囊性癌为舌下腺恶性肿瘤最常见的病理类型(56.7%);临床分期中Ⅲ期最常见(56.7%),局部复发和远处转移是患者死亡的主要原因,局部复发率为30.0%,远处转移率为26.7%。结论舌下腺恶性肿瘤以腺样囊性癌为主。手术是主要的治疗方法,原发灶切除配合颈部淋巴清扫术是达到良好治疗效果的关键,术后应适当辅助放化疗。

关键词: 恶性肿瘤, 舌下腺, 治疗

Abstract:

Objective To assess the clinical and histological features and therapeutic efficacy of 30 cases of malignant sublingual salivary gland tumors. Methods The clinicopathologic data of 30 patients with malignant sublingual salivary gland tumor were obtained from West China Hospital of Stomatology, Sichuan University from 1955 to 2005. Results There were 18 male and 12 female, and the average age of patients was 50.6 years old. Seventeen cases were adenoid cystic carcinoma, accounting for 56.7%. There were 17 cases clinically staged as Ⅲ, accounting for 56.7%. Distant metastasis and tumor recurrence were the main death reasons. The overall local recurrence rate was 30.0%, and distant metastasis rate was 26.7%. Conclusion Sublingual gland malignant tumors are rare and most of them are adenoid cystic carcinoma. Surgery is the main treatment option. The resection of the tumor accompanying with the neck dissection is the key method to achieve good therapeutic effect. The postoperative radiotherapy and chemotherapy should be adjuvant.

Key words: malignant tumor, sublingual gland, therapy