渐进性负荷对即刻植入种植体早期骨性结合的影响

华西口腔医学杂志

渐进性负荷对即刻植入种植体早期骨性结合的影响

班宇1，宫苹2，王少安2，刘晓光3，耿宁4，袁泉1

1.口腔生物医学工程教育部重点实验室，四川大学；2.四川大学华西口腔医院口腔种植科； 3.四川大学生物材料中心；4.四川大学华西口腔医院病理科，四川成都 610041

收稿日期:2006-06-25 修回日期:2006-06-25 出版日期:2006-06-20 发布日期:2006-06-20
通讯作者: 宫　苹，Tel: 028-85503579
作者简介:班　宇（1973-），女，新疆人，博士研究生
基金资助:
高等学校博士学科点专项科研基金资助项目（B120010610059）

Effects of Progressive Loading on Implants Placed　into Extraction Sockets: A Preliminary Study

BAN Yu1, GONG Ping2, WANG Shao-an2, LIU Xiao-guang3, GENG Ning4, YUAN Quan1

1. Key. Laboratory of Oral Biomedical Engineering Ministry of Education, Sichuan University, Chengdu 610041, China; 2. Dept. of Dental Implants, West China College of Stomatology, Sichuan University, Chengdu 610041, China; 3. Center of Biomaterial, Sichuan University, Chengdu 610041, China; 4. Dept. of Oral Pathology, West China College of Stomatology, Sichuan University, Chengdu 610041, China

Received:2006-06-25 Revised:2006-06-25 Online:2006-06-20 Published:2006-06-20

摘要/Abstract

摘要：

目的观察渐进性负荷后即刻植入种植体骨结合的早期X线及扫描电镜改变。方法选取4只健康雄性Beagle犬，于手术当天、术后第14天和第21天在麻醉下分别拔除双侧下颌第三前磨牙、第二前磨牙、第四前磨牙后即刻种植，共植入24颗种植体。术后24 h开始给予一侧下颌骨内种植体渐进性功能负荷，另一侧不给予负荷。分别于手术当天及术后第7、14、21、28天拍摄X线片，测量垂直骨吸收量（VBL）。实验第28天取材，进行扫描电镜观测。结果对照组VBL明显大于渐进性负荷组，二者比较有统计学意义（P＜0.05）。扫描电镜观察渐进性负荷组种植体表面骨形成速度明显快于对照组。结论即刻种植后给予渐进性垂直负荷不干扰种植体骨性结合过程，且可能有协同拔牙创的愈合作用，从而促进种植体骨性结合。

关键词: 即刻种植, 渐进性功能负荷, 骨性结合, 垂直骨吸收

Abstract:

Objective To study the effects of progressive loading on implants placed　into extraction sockets. Methods Bilateral 3rd, 4th and 2nd premolar of 4 beagle dogs were extracted and the implants were immediately inserted at 0, 14 and 21 days. The progressive loading procedure was conducted after 24 hours. The vertical bone loss（VBL） and the bone/biomaterials reactions were detected by X-ray and SEM. Results The VBL in control groups was larger than that for the experimental groups at 14, 21 and 28 days（P<0.05）. Scan electron microscopy detected that the mineralization speed of experimental groups was many times as faster as the control groups. Conclusion Progressive loading of implants placed　into extraction sockets can be performed without disturbing the osseointegration process. The potential of new bone formation in the extraction sockets and the physical strains can congenerously promote osseointegration.

Key words: immediately implanted, progressive loading, osseointegration, vertical bone loss

班宇;宫苹;王少安;刘晓光;耿宁;袁泉. 渐进性负荷对即刻植入种植体早期骨性结合的影响[J]. 华西口腔医学杂志.

BAN Yu1, GONG Ping2, WANG Shao-an2, LIU Xiao-guang3, GENG Ning4, YUAN Quan1. Effects of Progressive Loading on Implants Placed　into Extraction Sockets: A Preliminary Study[J]. West China Journal of Stomatology.

[1]	李春艳周延民王林李艳秋付丽宫琳. 阿仑膦酸钠对骨质疏松种植体骨结合影响的力学研究[J]. 华西口腔医学杂志, 2011, 29(03): 233-236.
[2]	朱光第,梁桂生. 种植体与非血管化植骨块结合的实验观察[J]. , 1998, 16(04): 0-.