可乐丽菲露SEBOND应用于Beagles犬直接盖髓术的组织学评价

华西口腔医学杂志

可乐丽菲露SEBOND应用于Beagles犬直接盖髓术的组织学评价

陆　玉1,刘天佳1,李秀群2,皮根莉1,李灏来1,杨锦波1

1.四川大学华西口腔医院　牙体牙髓病科,四川　成都610041; 2.四川大学华西医院　组织工程实验室,四川　成都610038

收稿日期:2005-10-25 修回日期:2005-10-25 出版日期:2005-10-20 发布日期:2005-10-20
通讯作者: 刘天佳,Tel:028-85502208
作者简介:陆　玉(1977-),女,陕西人,博士研究生

Histological Evaluation of Direct Pulp Capping with a Self-etching Adhesive and Calcium Hydroxide

LUYu1,LIUTian-jia1,LIXiu-qun2,PI Gen-li1,LIHao-lai1,YANGJin-bo1

1.Dept.ofDentistry andEndodontics,West China College ofSto- matology,Sichuan University,Chengdu610041,China;2.Tissue EngineeringLaboratory,West China College ofMedicine,Si- chuan University,Chengdu610038,China

Received:2005-10-25 Revised:2005-10-25 Online:2005-10-20 Published:2005-10-20

摘要/Abstract

摘要： 目的　将可乐丽菲露SE BOND用于beagles犬直接盖髓术后,进行组织学分级评价。方法　选择6只bea- gles犬共130颗健康牙齿,在颊面制备Ⅴ类洞并在洞底作人工穿髓孔,然后分为2组,实验组以可乐丽菲露SE BOND 盖髓,对照组以氢氧化钙盖髓。所有实验牙齿分别在盖髓后的第7、30、90天拔除,并进行组织学评价。结果　病理学评价显示,在7 d的观察期内2组的牙髓均呈轻度到中度的炎性反应,可乐丽菲露SE BOND组的炎性反应较氢氧化钙组轻,但其差别没有统计学意义。在30 d和90 d的观察期内2组均无明显的炎性反应,而牙本质桥的形成在氢氧化钙组显著多于可乐丽菲露SE BOND组,其差别有统计学意义(P<0·05)。结论　可乐丽菲露SE BOND对牙髓的刺激性较小,但诱导牙本质形成的能力较氢氧化钙弱。

关键词: 可乐丽菲露SE BOND, 直接盖髓术, 氢氧化钙

Abstract:

Objective　To evaluate the beagles′pulp response following direct pulp capping with Clearfil SE BOND (SB). Methods　130 sound teeth were used. 120 had their pulps mechanically exposed and were divided in two groups. In group A, teethwere capped with SB. In group B, teethwere capped with calcium hydroxide (CH). The left 10 teethwere used as control. After 7, 30 and 90 days, the teethwere extracted and processed for light microscopical examination.Results　In 7 day observa- tion period, inflammatory reaction in SB group was slighter than that of CHgroup, but the difference was statistical insignificant. In the 30 day and 90 day observation period, inflammatory reaction was slight in both groups, but specimens with dentin bridge formation was significantly less in SB group than in CH group (P<0.05).Conclusion　SB showed acceptable biocompatibility with pulp, but its ability to induce hard tissue barrier on pulp exposure is weaker than CH.

Key words: Clearfil SE BOND, direct pulp capping, calcium hydroxide

陆玉,刘天佳,李秀群,皮根莉,李灏来,杨锦波. 可乐丽菲露SEBOND应用于Beagles犬直接盖髓术的组织学评价[J]. 华西口腔医学杂志.

LUYu1,LIUTian-jia1,LIXiu-qun2,PI Gen-li1,LIHao-lai1,YANGJin-bo1. Histological Evaluation of Direct Pulp Capping with a Self-etching Adhesive and Calcium Hydroxide[J]. West China Journal of Stomatology.

[1]	张杨安,关为群,李群,刘玲玲. 辛伐他汀-胶原蛋白复合海绵用于大鼠磨牙直接盖髓的实验研究[J]. 华西口腔医学杂志, 2019, 37(2): 155-161.
[2]	范梦琳,何利邦,李继遥. 直接盖髓应用材料的研究进展[J]. 华西口腔医学杂志, 2018, 36(6): 675-680.
[3]	王敏永1 刘鹤1 李盛林2 秦满1. 三氧化矿物凝聚体对乳、恒牙牙髓细胞增殖和分化影响的比较[J]. 华西口腔医学杂志, 2015, 33(1): 75-79.
[4]	张晓芳林彦菊肇聿. 2种盖髓剂直接盖髓后大鼠牙髓诱导型一氧化氮合酶的表达变化[J]. 华西口腔医学杂志, 2011, 29(04): 420-423.
[5]	苏勤;叶玲;周学东;肖晓蓉;朱硃. 纳米羟磷灰石/聚酰胺66作为盖髓材料的体外抗菌作用[J]. 华西口腔医学杂志, 2007, 25(01): 26-28.
[6]	蒋月桂,孙沫逸,吴鸫,孙剑. 脱矿牙本质基质用于根尖诱导成形术的临床研究[J]. 华西口腔医学杂志, 2003, 21(06): 460-462.