华西口腔医学杂志

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受压前颌上颌骨缝变化的激光共聚焦扫描显微镜观察

王涛1,王大章2,徐慧芬2   

  1. 1.重庆医科大学附属口腔医院颌面外科,重庆630000; 2.四川大学华西口腔医学院口腔颌面外科教研室,四川成都610041
  • 收稿日期:2004-10-25 修回日期:2004-10-25 出版日期:2004-10-20 发布日期:2004-10-20
  • 通讯作者: 王涛.Tel:13983350829
  • 作者简介:王涛(1964-),男,重庆人,副教授,博士
  • 基金资助:
    四川省科技厅重点资助项目(G9906)

Experimental Study on the Microcosmic Cbanges of Compressed Premaxillary Suture with Laser Scarring Confocal Microscopy

WANG Tao1,WANG Da-zhang2,XU Hui feng2   

  1. 1.Dept.of Oral and Maxillofacial Surgery,Stomatology Hospital, Chongqing University of Medical Sciences,Chong Qing 630000, China; 2. Dept. of Oral and Maxillofacial Surgery, West China College of Stonmatology, Sichuan University, Chengdu 610041,China
  • Received:2004-10-25 Revised:2004-10-25 Online:2004-10-20 Published:2004-10-20

摘要:

目的探索前领骨术前主动加压矫治的合理性及规律。方法利用激光共聚焦扫描显微镜及三色荧光标记观察前领上领骨缝的发育及受压后骨缝结构的细微变化。结果加压3周后可见骨缝增宽,连接相邻骨端的纤维组织发生断裂;6周后可见有机成分增生,但局部结构紊乱;9一12周实验组与对照组结构无显著性差别。结论前领上领骨缝受压后存在“延滞效应”,受压后的骨缝在发育后期能够恢复正常状态,具有正常功能。

关键词: 骨缝, 生长发育, 激光共聚焦扫描显微镜

Abstract:

Objective The aim of this experiment is to know whether active orthopedic appliance is rationale to do presurgical treatment and seek some regularities. Methods Laser scanning confocal microscopy and triple fluorochrome labeling in bone were used to observe and study detailed changes occured in compressed suture systematically. Results Widened suture and broken fibres between the adjoining bones was observed at the 3ed week postoperatively. At the 3th week hyperplasia of organic tissue com- portents was also seen. At the 6 and 9th week there were no apparent differences among all groups no matter whether in control group or experimental groups. Conclusion Retarding injury of compressed suture and surrounding tissue hyperplasia exists. With  growth and development wounded suture will gradually assimilate to control group structurally and functionally.

Key words: suture, development, laserscaningconfocalmicroscopy