华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

615例小涎腺上皮性肿瘤的临床病理分析

李怡宁,何志秀,刘来奎,何华伟   

  1. 四川大学华西口腔医院 病理科,四川 成都 610041
  • 收稿日期:2004-06-25 修回日期:2004-06-25 出版日期:2004-06-20 发布日期:2004-06-20
  • 通讯作者: 李怡宁,Tel:13666113342
  • 作者简介:李怡宁(1978-),女,黑龙江人,助教,硕士

A Retrospective Study on 615 Cases of Minor Salivary Gland Tumors

LI Yi-ning, HE Zhi-xiu, LIULai-kui ,HEHua- wei   

  1. Dept. ofOral Pathology, West China College ofStomatology, Sichuan University, Chengdu610041, China
  • Received:2004-06-25 Revised:2004-06-25 Online:2004-06-20 Published:2004-06-20

摘要:

目的 探讨小涎腺上皮性肿瘤的临床病理特点。方法 对615例小涎腺上皮性肿瘤的部位分布、发病年龄、性别及组织学类型进行回顾性分析。结果 615例小涎腺上皮性肿瘤中腺瘤265例,癌350例,良恶性肿瘤之比为1∶1·3。良性肿瘤中以多形性腺瘤最为常见(81·1%),其次为肌上皮瘤(14·7%)。恶性肿瘤中以腺样囊性癌最常见(32·9%),其次为粘液表皮样癌(21·4%),腺癌(11·7%)。小涎腺上皮性肿瘤以腭部最为好发,分别占良、恶性肿瘤的77·0%和60.0%。腺瘤中女性患者(51·3%)稍多于男性(48·7%);小涎腺癌患者中男性(56·3%)多于女性 (43·7%)。小涎腺腺瘤患者平均发病年龄40·9岁,小涎腺癌平均发病年龄49·1岁,恶性肿瘤的发病年龄显著高于良性肿瘤(P<0·05)。结论 小涎腺上皮性肿瘤在病理类型构成比、部位、年龄、性别分布上具有其独到的特点。

关键词: 小涎腺, 肿瘤, 上皮性

Abstract:

Objective To analyse the clinical and pathological characterstics ofminor salivary gland tumors.Methods Aret- rospective analysis on 615 cases of intraoral minor salivary gland tumors from 1990~2002 with a confirmed pathologic diagnosis was carried out.Results In 615 cases ofminor salivary gland tumors, 265 caseswere benign, 350 casesmalignant. Pleomorphic adenoma was the most common entity and accounted for 81·1%of all benign tumors. Adenoid cystic carcinoma comprised 32·9% of the malignant sample and was the most frequent malignant tumor. The principal location was the palate. Female was a little more of the benign and a male prevalence was observed on the malignant tumor. The mean age of patients with benign and malig- nant tumors were 40·9 and 49·1 years old, respectively (P<0·05).Conclusion We consider extraordinary manifestation as histopathology, tumor, primary location, age and sex, presentingthe results of a reviewof our experiencewiththose minor salivary gland tumors.

Key words: minor salivary gland, tumors, epithelial