奶瓶龋的变链菌和乳杆菌水平及产酸分析

华西口腔医学杂志

奶瓶龋的变链菌和乳杆菌水平及产酸分析

钱虹,李成章,乐进秋

430079 武汉大学口腔医学院

收稿日期:2001-12-25 修回日期:2001-12-25 出版日期:2001-12-20 发布日期:2001-12-20

Relationship betweenStreptococcus mutans, Lactobacilusspp. and Lactate-producing Level and Nursing Bottle Caries

Qian Hong, Li Chengzhang, Yue Jinqiu

The StomatologyCollege of Wuhan University

Received:2001-12-25 Revised:2001-12-25 Online:2001-12-20 Published:2001-12-20

摘要/Abstract

摘要：

目的:探讨变链菌和乳杆菌与奶瓶龋的关系。方法:将2~215岁幼儿30名分为有龋组和无龋组,每组15 名。从上前牙唇面刮取牙菌斑,进行细菌培养,对变链菌和乳杆菌数目作出统计。取全口牙菌斑,用酶联仪进行乳酸分析。结果:奶瓶龋儿童有较高的变链菌和乳杆菌检出率,两者检出率均为100%。龋损部位的变链菌和乳杆菌数目为5110?1136和4182?1118,超过无龋儿童的相应部位。有龋儿童耐酸菌产乳酸量13629116nmol/OD?161194 nmol/OD高于无龋儿童。结论:变链菌和乳杆菌可能是奶瓶龋的主要病原菌。

关键词: 奶瓶龋, 变链菌, 乳杆菌, 乳酸

Abstract:

Objective:The study aimed to investigate the levels ofStreptococcus mutansandLactobacillusspp. as well as the relation- ship between lactate-productive and aciduric organisms and nursing bottle caries.Methods:Totally, 30 children of 2- to 2.5-year- old were divided into two groups, including the group of nursing bottle caries and the group of caries-free.Streptococcus mutans andLactobacillusspp. were isolated from dental plaque of all the children. The amount of lactate produced was measured with a microlitre plate reader.Results:The isolation frequency ofStreptococcus mutansandLactobacillusspp. were both 100 percent in the childrenwith nursing bottle caries, and that the composition of these bacteria from nursing bottle caries lesionswas higher than that of caries-free dental surface. Lactate-producing level was higher in the caries group than that of the caries-free group.Con- clusion:This study suggestsStreptococcus mutansandLactobacillusspp. may be the major pathogenic bacteria leading to nursing bottle caries.

Key words: nursing bottle caries, Streptococcus mutans, Lactobacillus spp., Lactate

钱虹,李成章,乐进秋. 奶瓶龋的变链菌和乳杆菌水平及产酸分析[J]. 华西口腔医学杂志.

Qian Hong, Li Chengzhang, Yue Jinqiu. Relationship betweenStreptococcus mutans, Lactobacilusspp. and Lactate-producing Level and Nursing Bottle Caries[J]. West China Journal of Stomatology.

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