华西口腔医学杂志

• 基础研究 • 上一篇    下一篇

三种根管消毒药物对慢性根尖周炎根管中内毒素水平的影响

谭红,胡涛,徐玉栋!610041   

  1. 610041 四川大学华西口腔医学院
  • 收稿日期:2001-08-25 修回日期:2001-08-25 出版日期:2001-08-20 发布日期:2001-08-20

Effects of Different Disinfactants on Levels of Endotoxin in Canals of Chronic Periapical Periodontitis

Tan Hong, Hu Tao, Xu Yudong   

  1. College of Stomatology, West China University of Medical Sciences
  • Received:2001-08-25 Revised:2001-08-25 Online:2001-08-20 Published:2001-08-20

摘要:

目的:探讨以甲硝唑为代表的抗厌氧菌药物在根管治疗中的应用前景。方法:选择慢性根尖周炎患牙共30 例,随机分别封甲酚醛、樟脑酚、甲硝唑各10例,封药前后分别取样,采用产色基质鲎试剂法检测内毒素含量,比较内毒素下降水平。结果:3组间内毒素下降水平无统计学差异。结论:根管封药可应用抗厌氧菌药物以治疗慢性根尖周炎。

关键词: 慢性根尖周炎, 内毒素, 甲硝唑

Abstract:

Objective:The objective of this study is to compare effects of formocresol, camphorated phenol and Ya Kan (metronedazole) on endotoxin levels in canals of chronic periapical periodontitis.Methods:Atotal of 30 patientswith chronic periacal periodontitis were selected from outpatients, and 10 cases eachwere randomly picked out to treat by sealingwith formoresol, camphorated phe- nol and Ya Kan respectively. All patientswere both sampled before and after sealing of these disinfectants, and chromogenic sub- strate method of limulus amebocyte lysate (LAL) testwas used to measure levels of endotoxin.Results:The effects of Ya Kan, formocresol and camphorated phenol on levels of endotoxin did not showed significant difference.Conclusion:Some anti-anaerobic bacterial drugs can be used to treat chronic periapical periodontitis.

Key words: chronic periapical periodontitis, endotoxin, metronedazole