华西口腔医学杂志
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谭红,胡涛,徐玉栋!610041
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Tan Hong, Hu Tao, Xu Yudong
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目的:探讨以甲硝唑为代表的抗厌氧菌药物在根管治疗中的应用前景。方法:选择慢性根尖周炎患牙共30 例,随机分别封甲酚醛、樟脑酚、甲硝唑各10例,封药前后分别取样,采用产色基质鲎试剂法检测内毒素含量,比较内毒素下降水平。结果:3组间内毒素下降水平无统计学差异。结论:根管封药可应用抗厌氧菌药物以治疗慢性根尖周炎。
关键词: 慢性根尖周炎, 内毒素, 甲硝唑
Abstract:
Objective:The objective of this study is to compare effects of formocresol, camphorated phenol and Ya Kan (metronedazole) on endotoxin levels in canals of chronic periapical periodontitis.Methods:Atotal of 30 patientswith chronic periacal periodontitis were selected from outpatients, and 10 cases eachwere randomly picked out to treat by sealingwith formoresol, camphorated phe- nol and Ya Kan respectively. All patientswere both sampled before and after sealing of these disinfectants, and chromogenic sub- strate method of limulus amebocyte lysate (LAL) testwas used to measure levels of endotoxin.Results:The effects of Ya Kan, formocresol and camphorated phenol on levels of endotoxin did not showed significant difference.Conclusion:Some anti-anaerobic bacterial drugs can be used to treat chronic periapical periodontitis.
Key words: chronic periapical periodontitis, endotoxin, metronedazole
谭红,胡涛,徐玉栋!610041. 三种根管消毒药物对慢性根尖周炎根管中内毒素水平的影响[J]. 华西口腔医学杂志.
Tan Hong, Hu Tao, Xu Yudong. Effects of Different Disinfactants on Levels of Endotoxin in Canals of Chronic Periapical Periodontitis[J]. West China Journal of Stomatology.
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