双膦酸盐相关性颌骨坏死并发腕部舟状骨骨髓炎1例

doi:10.7518/hxkq.2019.02.017

华西口腔医学杂志 ›› 2019, Vol. 37 ›› Issue (2): 224-228.doi: 10.7518/hxkq.2019.02.017

• 病例报告 • 上一篇

双膦酸盐相关性颌骨坏死并发腕部舟状骨骨髓炎1例

孙照薇¹,李志勇¹(),余丹²,朱洁颖¹,张伊殿²,朱鑫美¹

1.浙江大学医学院附属口腔医院口腔颌面外科
2.浙江大学医学院附属第一医院口腔颌面外科,杭州 310006

收稿日期:2018-06-10 修回日期:2018-11-08 出版日期:2019-04-01 发布日期:2019-04-28
通讯作者: 李志勇 E-mail:hxlzy2002@zju.edu.cn
作者简介:孙照薇,硕士,E-mail： 21618009@zju.edu.cn

Bisphosphonate-related osteonecrosis of the jaw complicated with wrist scaphoid osteomyelitis: a case report

Zhaowei Sun¹,Zhiyong Li¹(),Dan Yu²,Jieying Zhu¹,Yidian Zhang²,Xinmei Zhu¹

1.Dept. of Oral and Maxillofacial Surgery, Stomatology Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China
2.Dept. of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310006, China

Received:2018-06-10 Revised:2018-11-08 Online:2019-04-01 Published:2019-04-28
Contact: Zhiyong Li E-mail:hxlzy2002@zju.edu.cn

摘要/Abstract

摘要：

双膦酸盐类药物可以抑制破骨细胞功能,使颌骨骨密度升高,血流减少,发生骨坏死。双膦酸盐类药物相关性骨坏死多发于颌骨。本文报道1例双膦酸盐相关性颌骨坏死并发腕部舟状骨骨髓炎,并结合文献讨论双膦酸盐药物性颌骨坏死的发病机制、治疗与预防等。

关键词: 双膦酸盐, 颌骨坏死, 舟状骨骨髓炎, 唑来膦酸

Abstract:

Bisphosphonates can directly inhibit osteoclasts, which may lead to increased bone density, reduced blood flow, and osteonecrosis of the jaw. Bisphosphonate-related osteonecrosis is usually observed in the jaw bone. In this article, we report a patient with bisphosphonate-related osteonecrosis of the jaw (BRONJ) complicated with wrist scaphoid osteo-myelitis. Furthermore, we introduce the pathogenesis, treatment, and prevention of BRONJ.

Key words: bisphosphonate, osteonecrosis of the jaw, scaphoid osteomyelitis, zoledronic acid

中图分类号:

R782.3

孙照薇,李志勇,余丹,朱洁颖,张伊殿,朱鑫美. 双膦酸盐相关性颌骨坏死并发腕部舟状骨骨髓炎1例[J]. 华西口腔医学杂志, 2019, 37(2): 224-228.

Zhaowei Sun,Zhiyong Li,Dan Yu,Jieying Zhu,Yidian Zhang,Xinmei Zhu. Bisphosphonate-related osteonecrosis of the jaw complicated with wrist scaphoid osteomyelitis: a case report[J]. West China Journal of Stomatology, 2019, 37(2): 224-228.

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参考文献 15

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双膦酸盐相关性颌骨坏死并发腕部舟状骨骨髓炎1例

Bisphosphonate-related osteonecrosis of the jaw complicated with wrist scaphoid osteomyelitis: a case report

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