单侧完全性唇腭裂患者牙龄骨龄相关性的研究

doi:10.7518/hxkq.2019.02.010

华西口腔医学杂志 ›› 2019, Vol. 37 ›› Issue (2): 180-186.doi: 10.7518/hxkq.2019.02.010

单侧完全性唇腭裂患者牙龄骨龄相关性的研究

房晓旭^1,²,范存晖^1,²(),薛青³,许涛^1,²,肖文林⁴,田忠辉^1,²,徐晓琳^1,²

1.青岛大学附属医院口腔正畸科
2.青岛大学口腔医学院,青岛 266003
3.泰山医学院附属医院口腔正畸科,泰安 271000
4.青岛大学附属医院口腔医学中心,青岛 266003

收稿日期:2018-11-12 修回日期:2019-01-26 出版日期:2019-04-01 发布日期:2019-04-28
通讯作者: 范存晖 E-mail:kysfch@126.com
作者简介:房晓旭,硕士,E-mail： 1277682257@qq.com
基金资助:
山东省科技发展计划项目(2014GGH218012)

Association between cervical vertebral maturation stages and dental calcification stages in patients with unilateral complete cleft lip and palate

Xiaoxu Fang^1,²,Cunhui Fan^1,²(),Qing Xue³,Tao Xu^1,²,Wenlin Xiao⁴,Zhonghui Tian^1,²,Xiaolin Xu^1,²

1. Dept. of Orthodontics, The Affiliated Hospital of Qingdao University, Qingdao 266003, China
2.School of Stomatology, Qingdao University, Qingdao 266003, China
3.Dept. of Orthodontics, The Affiliated Hospital of Taishan Medical University, Taian 271000, China
4.Oral Medicine Centre, Affiliated Hospital of Qingdao University, Qingdao 266003, China)

Received:2018-11-12 Revised:2019-01-26 Online:2019-04-01 Published:2019-04-28
Contact: Cunhui Fan E-mail:kysfch@126.com
Supported by:
Shandong Province Science and Technology Development Program(2014GGH218012)

摘要/Abstract

摘要：

目的探讨单侧完全性唇腭裂（UCLP）患者牙龄（DCS）和颈椎骨龄（CVMS）间关系,为唇腭裂（CLP）患者选择治疗时间提供理论基础。方法选择UCLP患者123名,非CLP患者215名。通过Demirjian法评估非CLP患者下颌左侧和UCLP患者下颌双侧尖牙,前磨牙及第二磨牙的DCS;通过Baccetti法观测CVMS。将DCS和CVMS分布行Spearman相关分析,并对相关性进行比较。结果非CLP患者和UCLP患者的所有DCS和CVMS均具有显著相关性（非CLP患者r=0.762~0.864,P<0.05;UCLP患者r=0.809~0.914,P<0.05）。其中,UCLP患者下颌第一前磨牙DCS和CVMS相关性最高。除UCLP女性前磨牙外,其余牙齿DCS和CVMS的相关性同非CLP患者间无统计学差异（P>0.05）。结论 DCS可以作为判定UCLP患者生长发育的生物学指标。其中,下颌第一前磨牙的DCS和CVMS相关性最大。

关键词: 单侧完全性唇腭裂, 牙龄, 颈椎骨龄

Abstract:

Objective The purpose of the study is to investigate the relationship between dental calcification stages (DCS) and cervical vertebral maturation stages (CVMS) in patients with unilateral complete cleft lips and palates (UCLP) and to provide a theoretical basis for the treatment time selection of cleft lip and palate (CLP) patients. Methods A total of 123 UCLP patients and 215 non-CLP subjects were selected. The DCS of the left mandibular canine, premolar, and second molar in non-CLP subjects and on both cleft sides of UCLP patients were assessed utilizing the Demirjian method. CVMS was observed utilizing the Baccetti method. The results were analyzed by Spearman rank correlation, and the correlation coefficients were compared. Results There was a correlation between the CVMS and the DCS of the left mandibular canine, the first premolar, the second premolar, and the second molar in the non-CLP subjects and on both cleft sides of the UCLP patients (r=0.762-0.864, P<0.05; r=0.809-0.914, P<0.05, respectively). The correlation between the CVMS and the DCS of the mandibular first premolar was highest among the UCLP patients. Except for the first and the second premolars of UCLP females, the correlation between the DCS and the CVMS of the other teeth did not differ among the non-CLP subjects (P>0.05). Conclusion DCS can be utilized as a biological index to determine the growth development statuses. The correlation between the CVMS and the DCS of the mandibular first premolar was the highest.

Key words: unilateral complete cleft lip and palate, dental calcification stages, cervical vertebral maturation stages

中图分类号:

R783.5

房晓旭,范存晖,薛青,许涛,肖文林,田忠辉,徐晓琳. 单侧完全性唇腭裂患者牙龄骨龄相关性的研究[J]. 华西口腔医学杂志, 2019, 37(2): 180-186.

Xiaoxu Fang,Cunhui Fan,Qing Xue,Tao Xu,Wenlin Xiao,Zhonghui Tian,Xiaolin Xu. Association between cervical vertebral maturation stages and dental calcification stages in patients with unilateral complete cleft lip and palate[J]. West China Journal of Stomatology, 2019, 37(2): 180-186.

图/表 6

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参考文献 28

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CVMS分期	DCS分期	尖牙		第一前磨牙		第二前磨牙		第二磨牙
CVMS分期	DCS分期	男	女	男	女	男	女	男	女
CS1	C	0	0	0	0	0	0	18.2	10
	D	9.1	20	9.1	30	18.2	30	54.5	40
	E	54.5	50	81.8	70	81.8	70	27.3	50
	F	36.4	30	9.1	0	0	0	0	0
	G	0	0	0	0	0	0	0	0
	H	0	0	0	0	0	0	0	0
CS2	C	0	0	0	0	0	0	0	10
	D	0	0	6.7	20	20	30	46.7	40
	E	53.3	30	53.3	60	53.3	70	26.7	50
	F	40	70	40	20	20	0	20	0
	G	6.7	0	0	0	6.7	0	6.7	0
	H	0	0	0	0	0	0	0	0
CS3	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	30	6.3	0
	E	12.5	30	18.8	28.6	25	70	37.5	0
	F	62.5	70	50	57.1	50	0	31.3	42.9
	G	18.8	0	18.8	14.3	18.8	0	25	57.1
	H	6.3	0	12.5	0	6.2	0	0	0
CS4	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	0	0	0
	E	0	30	0	0	0	0	16.7	0
	F	41.7	70	41.7	57.1	58.3	57.1	41.7	42.9
	G	33.3	0	25	14.3	25	14.3	41.7	57.1
	H	25	0	33.3	28.6	16.7	28.6	0	0
CS5	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	0	0	0
	E	0	0	0	0	0	0	0	0
	F	0	0	0	0	12.5	0	37.5	0
	G	37.5	20	25	40	25	40	62.5	60
	H	62.5	80	75	60	62.5	60	0	40
CS6	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	0	0	0
	E	0	0	0	0	0	0	0	0
	F	0	0	0	0	0	0	0	0
	G	0	20	0	0	0	0	22.2	12.5
	H	100	80	100	100	100	100	77.8	87.5

CVMS分期	DCS分期	尖牙		第一前磨牙		第二前磨牙		第二磨牙
CVMS分期	DCS分期	男	女	男	女	男	女	男	女
CS1	C	0	0	0	0	0	0	18.2	30
	D	9.1	30	18.2	40	27.3	40	54.5	30
	E	81.8	60	81.8	60	72.7	60	27.3	40
	F	9.1	10	0	0	0	0	0	0
	G	0	0	0	0	0	0	0	0
	H	0	0	0	0	0	0	0	0
CS2	C	0	0	0	0	0	0	0	10
	D	0	20	18.2	30	20	30	46.7	40
	E	53.3	60	81.8	70	66.7	70	26.7	50
	F	40	20	0	0	6.7	0	26.7	0
	G	6.7	0	0	0	6.7	0	0	0
	H	0	0	0	0	0	0	0	0
CS3	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	20	0	12.5	14.3
	E	53.3	28.6	43.8	37.5	66.7	37.5	37.5	28.6
	F	40	57.1	43.8	62.5	6.7	62.5	31.3	28.6
	G	6.7	14.3	6.3	0	6.7	0	18.8	28.6
	H	0	0	6.3	0	0	0	0	0
CS4	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	0	0	0
	E	8.3	0	0	0	16.7	0	25	0
	F	33.3	21.4	50	71.4	58.3	71.4	50	57.1
	G	41.7	64.3	33.3	14.3	16.7	14.3	25	42.9
	H	16.7	14.3	16.7	14.3	8.3	14.3	0	0
CS5	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	0	0	0
	E	0	0	0	0	0	0	0	0
	F	0	0	50	20	12.5	20	25	0
	G	25	20	33.3	20	25	20	75	60
	H	75	80	16.7	60	62.5	60	0	40
CS6	C	0	0	0	0	0	0	0	0
	D	0	0	0	0	0	0	0	0
	E	0	0	0	0	0	0	0	0
	F	0	0	0	0	0	0	0	0
	G	0	0	0	0	0	0	33.3	12.5
	H	100	100	100	100	100	100	66.7	87.5

性别	牙位	r_N	r_NC	Z值	P值
男	尖牙	0.852*	0.816*	0.756 7	>0.05
	第一前磨牙	0.788*	0.846*	1.120 9	>0.05
	第二前磨牙	0.812*	0.839*	0.541 5	>0.05
	第二磨牙	0.864*	0.809*	1.178 3	>0.05
女	尖牙	0.786*	0.877*	1.756 8	>0.05
	第一前磨牙	0.762*	0.905*	2.900 8	<0.01
	第二前磨牙	0.781*	0.901*	2.501 1	<0.05
	第二磨牙	0.815*	0.889*	1.603 4	>0.05

性别	牙位	r_N	r_C	Z值	P值
男	尖牙	0.852*	0.830*	0.459 4	>0.05
	第一前磨牙	0.788*	0.861*	1.473 4	>0.05
	第二前磨牙	0.812*	0.843*	0.628 6	>0.05
	第二磨牙	0.864*	0.817*	1.027 8	>0.05
女	尖牙	0.786*	0.875*	1.706 8	>0.05
	第一前磨牙	0.762*	0.914*	3.204 2	<0.01
	第二前磨牙	0.781*	0.907*	2.692 3	<0.01
	第二磨牙	0.815*	0.898*	1.863 4	>0.05

单侧完全性唇腭裂患者牙龄骨龄相关性的研究

Association between cervical vertebral maturation stages and dental calcification stages in patients with unilateral complete cleft lip and palate

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