华西口腔医学杂志

• 临床研究 • 上一篇    下一篇

兰州地区唾液幽门螺杆菌感染状况分析

郭瑞1  车团结2  居军3  杨森1  何祥一4  张莹5   

  1. 1.兰州大学第一临床医学院检验科;2.兰州大学生命科学院细胞生物研究所;
    3.甘肃省人民医院检验中心;4.兰州大学口腔医学院口腔修复学教研室;
    5.兰州百源基因技术有限公司,兰州 730000
  • 出版日期:2014-08-01 发布日期:2014-08-01
  • 通讯作者: 居军,主任检验师,学士,E-mail:jjwork@163.com
  • 作者简介:郭瑞,初级检验师,硕士,E-mail:guoruilanzhou@163.com

Analysis of the infection status of saliva Helicobacter pylori in Lanzhou

Guo Rui1, Che Tuanjie2, Ju Jun3, Yang Sen1, He Xiangyi4, Zhang Ying5   

  1. 1. Dept. of Clincal Laboratory, The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China; 2. Institute of Cell Biology, School of Life Science, Lanzhou University, Lanzhou 730000, China; 3. Dept. of Clinical Laboratory, Gansu Province People Hospital, Lanzhou 730000, China; 4. Dept. of Prosthodontics, School of Stoma-tology, Lanzhou University, Lanzhou 730000, China; 5. Baiyuan Genetic Technology Company of Lanzhou, Lanzhou 730000, China
  • Online:2014-08-01 Published:2014-08-01

摘要:

目的  分析兰州地区人群唾液幽门螺杆菌的感染状况,为防治幽门螺杆菌提供科学依据。方法  收集兰州地区 941例患者的唾液标本进行幽门螺杆菌的细菌学培养,并进行革兰染色镜检及生化特性鉴定。对不同口腔卫生情况、口腔疾病、性别、城乡、年龄段患者的唾液幽门螺杆菌感染率及生长情况进行分析。结果  兰州地区人群唾液幽门螺杆菌的阳性率为42.72%。不同口腔卫生和口腔疾病情况下,患者唾液幽门螺杆菌的阳性率均存在统计学差异(P<0.05)。男性与女性的唾液幽门螺杆菌阳性率分别为38.45%、47.89%,女性阳性率高于男性(P=0.004,χ2=8.492);城市、农村人群的唾液幽门螺杆菌阳性率分别为33.99%、50.93%,农村人群的阳性率高于城市人群(P=0.000,χ2=27.551)。10~59岁各年龄段唾液幽门螺杆菌阳性率基本上变化不大,呈平坦趋势,60岁之后呈上升趋势。不同年龄段唾液幽门螺杆菌生长量无统计学差异(P=0.086)。结论  兰州地区人群的唾液幽门螺杆菌阳性率与其口腔卫生、口腔疾病、性别、年龄及生活环境等均相关。

关键词: 幽门螺杆菌, 细菌培养, 兰州

Abstract:

Objective  To determinetheprevalenceofsaliva Helicobacter pylori inLanzhou andinvestigate Helicobacter pylori-related diseases. Methods  Helicobacter pylori was detected through bacterial culture, Gram stain microscopy, and urease test from saliva samples collected from 941 residents of Lanzhou. The infection rate and growth of Helicobacter pylori among the residents were analyzed in terms of different oral health conditions, oral disease, gender, urban and rural status, and age. Results The rate of Helicobacter pylori-positive saliva in Lanzhou was 42.72%. The status of Helicobacter pylori infection showed significant difference among subjects with different oral hygiene and oral diseases. The rate of Helicobacter pylori-positive saliva among females was 47.89%, which was greater compared with the rate among males (38.45%, P=0.004, χ2=8.492). The rate of Helicobacter pylori-positive saliva in the town was 33.99%, which was less than the rate for the villages (50.93%, P=0.000, χ2=27.551). The rate of Helicobacter pylori-positive saliva among residents aged 10 to 59 showed a flat trend with no significant differences. However, the rate of Helicobacter pylori-positive saliva among residents over 60 years old showed a significantincrease. Nosignificant difference was foundinthegrowth of saliva Helicobacter pylori (P=0.086). Conclusion The rate of Helicobacter pylori-positive saliva isrelated to thesubjects’ oralhygiene, oral disease, gender, age, and living conditions. 

Key words: Helicobacter pylori,  , bacterial culture,  , Lanzhou