华西口腔医学杂志

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氟化钠甘油过敏1例

马继红   

  1. 山东大学千佛山校区医院口腔科, 济南250061
  • 收稿日期:2012-04-25 修回日期:2012-04-25 出版日期:2012-04-01 发布日期:2012-04-01
  • 通讯作者: 马继红,Tel:13969129118
  • 作者简介:马继红(1959—),女,山东人,主治医师

Allergy caused by sodium fluoride glycerin: A case report

Ma Jihong   

  1. Dept. of Stomatology, Qianfoshan Campus Hospital, Shandong University, Jinan 250061, China
  • Received:2012-04-25 Revised:2012-04-25 Online:2012-04-01 Published:2012-04-01
  • Contact: Ma Jihong,Tel:13969129118
  • About author:Ma Jihong(1959—),女,山东人,主治医师

摘要:

近年来药物过敏引起的口腔黏膜溃疡越来越多,但氟化钠甘油过敏引起的溃疡却极少见。山东大学千佛山校区医院遇到氟化钠甘油过敏1例,氟化钠甘油治疗后患者口腔黏膜充血水肿明显,颊、腭黏膜有大量红色粟粒状颗粒,3 h后出现吞咽困难,但无呼吸困难,次日出现口腔黏膜大面积溃疡。治疗7 d后患者痊愈,氟化钠敏感试验结果为阳性。

关键词: 氟化钠甘油, 药物过敏, 脱敏治疗

Abstract:

In recent years, though more and more ulcerations of oral mucosa caused by allergy to drug occurred clinically, allergy to sodium fluoride glycerin is extremely rare. A case of allergy to sodium fluoride glycerin occurred in Qianfoshan Campus Hospital of Shandong University. After treatment by sodium fluoride glycerin, there was mucosal edema, a large number of red miliary granules in buccal and palatal mucosa. After 3 hours, there were swallowing difficulties, but no breathing difficulties. Next day large ulcers of oral mucosa developed. The patient was cured 7 days after treatment. Fluoride-sensitive test result was positive.

Key words: sodium fluoride glycerin, drug allergy, desensitization therapy